Thioguanine CAS 154-42-7: Detailed Overview on Properties and Applications
ProcurenetShort description
Thioguanine – CAS 154-42-7
- Chemical Formula: C5H5N5S, with a pale yellow crystalline form.
- Applications: Primarily utilized for its dose-dependent inhibition of stimulated expression of TRAIL protein, with potential diverse therapeutic effects.
- Chemical Properties: Stable under standard temperatures and pressures and it possesses a molecular weight of 167.19. It’s also soluble.
- Safety: Always refer to the provided Safety Data Sheet for any safety concerns and handling procedures.
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Procurenet Team Tshim Sha Tsui
Hong Kong
3 years
Description
Thioguanine CAS 154-42-7: Comprehensive Overview on Chemical Properties, Usage, and Safety Information
Thioguanine, with the CAS number 154-42-7, is a widely recognized compound for its significant applications in the medical domain. This compound, appearing as a pale-yellow crystalline powder, is characterized by its specific physical and chemical properties.
- Molecular weight: Thioguanine's molecular weight, indicating the mass of one molecule of the compound, is 167.19.
- Density: Thioguanine has a density value of 2.08 g/cm3 reflecting its quality and consistency.
- Boiling Point: The boiling point of this compound is 123°C at 29 torr, indicating the temperature where it shifts from liquid to gas under ordinary atmospheric conditions.
- Melting Point: It changes state from solid to liquid at 360°C, which significantly influences its behavior during processing.
- Flash Point: The flash point of thioguanine is 356°C. This temperature signifies when the compound can catch fire in air, hence it is vital to take note for safety considerations.
- Solubility: Thioguanine exhibits superior solubility properties, emphasizing its ability to dissolve efficiently.
- Stability: Owing to its stability under normal temperatures and pressures, Thioguanine presents a favorable option for various applications.
Thioguanine finds prominent applications in the medical industry, owing to its ability to stimulate the expression of TRAIL protein, causing a dose-dependent inhibition. Also known as 6-Thioguanine, this compound is commonly used in chemotherapy to treat acute leukemia, giving it a niche in the pharmacological space.
It is crucial to adhere to the safety data sheet that outlines detailed information about Thioguanine's potential hazards, safe handling instructions, and what to do in case of any accidental contact. For best results and longevity, always store this compound at room temperature.
