Simvastatin: Potent Control of Cholesterol Levels & Reduce Triglycerides
ProcurenetShort description
Simvastatin is a critical cholesterol and triglyceride regulator and an integral part of the statin drug class. It primarily works by:
- Inhibiting an enzyme responsible for cholesterol production in the liver.
- Reducing LDL (bad cholesterol) levels.
- Boosting HDL (good cholesterol) levels.
- Lowering triglyceride levels in the blood.
This medication’s proper use can aid in preventing cardiovascular diseases. Its formulated ingredients comprise Simvastatin, Lactose monohydrate, Microcrystalline cellulose, Croscarmellose sodium, Hydroxypropyl cellulose, and Magnesium stearate. The drug is administered orally. Prior consultation with your doctor is necessary before starting the treatment.
-
Procurenet Team Tshim Sha Tsui
Hong Kong
3 years
Description
Simvastatin is a potent medication designed for the control of cholesterol and triglyceride levels in the blood, providing pivotal support in combating cardiovascular diseases. As a distinguished member of the statin family, Simvastatin exerts a strong inhibitory effect on 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA reductase), an enzyme integral to cholesterol production in the liver.
- Effective decrease in low-density lipoprotein (LDL) cholesterol, known as 'bad' cholesterol.
- Facilitates the increase of high-density lipoprotein (HDL) cholesterol, popularly known as 'good' cholesterol.
- Potent reduction in the levels of blood triglycerides.
- Decreases the risk and progression of cardiovascular diseases.
Simvastatin's active pharmaceutical ingredient is simvastatin itself, compounded with several excipients for optimal delivery and absorption, including Lactose Monohydrate, Microcrystalline Cellulose, Croscarmellose Sodium, Hydroxypropyl Cellulose, and Magnesium Stearate.
The medication should be taken orally, preferably as a single dose in the evening. It can be taken with or without food based on your physician's advice. A balanced diet and regular exercise further complement the action of Simvastatin, ensuring comprehensive management of your cholesterol and triglyceride levels.
Key precautions with Simvastatin include abstaining from grapefruit or grapefruit juice, which can increase the likelihood of side effects. It is also critical to discuss your medical history and any allergies with your doctor before initiating Simvastatin. Simvastatin should not be used without medical approval if you are pregnant or breastfeeding.
Chemical Profile
Molecular Formula: C25H38O5Molecular Weight: 418.57 g/molCAS Number: 79902-63-9Canonical SMILES: CCC(C)(C)C(=O)OC1CC2C3CCC4=CC(=O)CCC4(C)C3(F)C(CC)CC2C1CDensity: 1.18 g/cm3LogP: 4.1
Safety Information
GHS Classification: Health hazardPrecautionary Statements: P280 - Wear protective gloves/protective clothing/eye protection/face protection. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
