MISSION® esiRNA targeting mouse Ostm1 | Highly Effective Gene Silencing

The MISSION® esiRNA targeting mouse Ostm1 is a highly effective product that enables specific gene silencing in mice. This innovative esiRNA product is designed to efficiently knockdown the Ostm1 gene expression, making it an essential tool for researchers studying bone-related diseases and osteoclast differentiation.

Product Features:

• Designed for highly effective gene silencing
• Targets the Ostm1 gene
• Specifically designed for mouse models
• Enables efficient knockdown of the Ostm1 gene expression
• Essential tool for studying bone-related diseases and osteoclast differentiation

Product Details:

The MISSION® esiRNA targeting mouse Ostm1 is meticulously designed to provide researchers with a reliable and efficient tool for investigating the role of Ostm1 in bone-related diseases and osteoclast differentiation. The product offers a targeted approach to gene silencing, ensuring accurate and specific silence of the Ostm1 gene expression in mice. Through this targeted gene knockdown, researchers can gain valuable insights into the molecular mechanisms underlying the development and progression of various bone disorders.

Composition:

The MISSION® esiRNA targeting mouse Ostm1 is composed of small interfering RNAs (siRNAs) specifically designed to effectively bind and degrade the mRNA transcripts of the Ostm1 gene. These siRNAs are chemically modified to enhance stability and specificity, ensuring efficient gene knockdown and preventing off-target effects. The formulation also includes delivery reagents that facilitate the uptake of the esiRNA by cells, maximizing its effectiveness.

Applications:

• Investigation of bone-related diseases
• Study of osteoclast differentiation
• Analysis of molecular mechanisms underlying bone disorders
• Gene function studies
• Validation of therapeutic targets

Instructions for Use:

The MISSION® esiRNA targeting mouse Ostm1 is provided as a ready-to-use solution. Prior to use, ensure proper storage at -20°C to maintain product stability. To perform gene silencing experiments, follow these general guidelines:

1. Prepare the desired cell culture or animal model.
2. Thaw the MISSION® esiRNA targeting mouse Ostm1 solution on ice.
3. Add the appropriate volume of the esiRNA solution to the cell culture or administer it to animal models according to the desired concentration.
4. In order to optimize the knockdown efficiency, conduct a dose-response experiment by testing various concentrations of the esiRNA.
5. Incubate cells or allow animal models to recover for a specified period of time depending on the experimental design.
6. Proceed with downstream analysis to assess the gene knockdown efficiency or phenotype changes resulting from Ostm1 silencing.

Safety Information:

The MISSION® esiRNA targeting mouse Ostm1 is intended for research use only. It is not intended for therapeutic purposes or human consumption. Handle the product with appropriate laboratory safety measures, including the use of gloves, lab coats, and eye protection. For detailed safety information, refer to the Material Safety Data Sheet (MSDS) provided with the product.

Technical Support:

For any technical inquiries or assistance regarding the use of the MISSION® esiRNA targeting mouse Ostm1, please contact our technical support team. Our experts are well-versed in the applications, handling, and troubleshooting of this product and will be happy to assist you.

Related Products:

Explore our wide range of related products that can complement your research on bone-related diseases and osteoclast differentiation:

• MISSION® esiRNA targeting mouse RANK
• MISSION® esiRNA targeting mouse Ctsk
• MISSION® esiRNA targeting mouse Acp5

References:

For further information about the applications and scientific evidence supporting the use of MISSION® esiRNA targeting mouse Ostm1, please refer to the following peer-reviewed publications:

• Reference 1
• Reference 2
• Reference 3

Download Resources:

For additional technical documents related to the MISSION® esiRNA targeting mouse Ostm1, please find the following resources available for download:

• Product Datasheet
• Protocol
• Application Note