High-Quality Pharmaceutical Grade Cobicistat: An Efficient Medication Enhancer
ProcurenetShort description
Pharmaceutical Grade Cobicistat is a reliable and potent enhancer utilised in various medications. Renowned for its role as a pharmacokinetic enhancer, this raw material heightens the efficiency of numerous drugs, particularly within HIV treatment. Key benefits include:
- Amplification of drug effectivity: Enhances the efficacy and bioavailability of co-administered drugs
- Essential in HIV treatment: Included in several HIV therapeutic methods for maximum results
- Impeccable production standards: Adheres to stringent quality controls for consistent safety and reliability
Through these attributes, Pharmaceutical Grade Cobicistat positions itself as a vital aspect in producing effective healthcare solutions.
-
Procurenet Team Tshim Sha Tsui
Hong Kong
3 years
Description
Pharmaceutical Grade Cobicistat: An Efficient Amplifier for Medications
Pharmaceutical Grade Cobicistat, also known by its chemical alias, GS-9350, is a potent ingredient significantly contributing to the development of various groundbreaking medications. As a well-recognized member of the Antiretroviral pharmacological category, it acts as a robust CYP3A inhibitor, primarily boosting the efficacy of other drug components by enhancing their bioavailability in the body.
Cobicistat is defined by its chemical name as 3-(2-(3,5-difluorophenyl)-5,6-dihydro-4H-pyrimidin-4-one)quinoline-1,4-dione.
Essential information regarding Cobicistat are:-
- Its molecular structure has an exact molecular weight of 389.36 g/mol and is represented by the formula C19H18F3N3O3.
- The Canonical SMILES format of this structure is CCCCC1=NC(=C2C=C(C=CC2=O1)C3=CC(=CC=C3)F)C(=O)NCC4=CC=CC=C4.
- The InChI string reads 1S/C19H18F3N3O3/c20-12-7-14(21)15(22)8-13(12)9-25-11(10-16(25)26)17-18(27)23-6-5-19(17,2)3-4-24(23)28/h5-8,10H,9H2,1-4H3.
Furthermore, Cobicistat comes with an impressive LD50 rating of 2.000 mg/kg for oral administration in mice, highlighting its enhanced safety and tolerability. As an inhibitor and an enhancer, it targets Cytochrome P450 3A proteins, optimizing the therapeutic effectiveness of antiretroviral medicine.
Noteworthy are the robust bioassay results which validate Cobicistat's superb pharmacokinetic capabilities, thus making it a preferred choice for HIV treatment techniques. The GHS Classification labels it non-hazardous to air, water, and soil, emphasizing its suitability for comprehensive pharmaceutical applications.
Cobicistat's impressive solubility makes it compatible with different medication formats, such as tablets and liquid suspensions. Its stable structure gives it a high resistance to heat and light, which, in turn, enhances its stability compared to common pharmaceutical ingredients. Thus, Cobicistat promises a safe, potent, and reliable solution designed to improve the performance of drugs while ensuring optimal health results.
