1,10 Phenanthroline Monohydrate: A Versatile Compound for Multiple Industries
ProcurenetShort description
1,10 Phenanthroline Monohydrate: A Multi-purpose Compound for Research and Determination
- 1,10 Phenanthroline Monohydrate (CAS no. 5144-89-8): a pharmaceutical-grade raw material in the form of white crystalline powder; soluble in water, benzene, alcohol, and acetone.
- Primarily used for determining iron content via spectrophotometry while also having significant value in DNA damage studies and anticancer research.
- It’s unique in forming stable and useful complexes with transition metals. The chelates formed with copper display DNA cutting activity.
- While handling, ensure to follow safety precautions as detailed in the Safety Data Sheet (SDS).
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Procurenet Team Tshim Sha Tsui
Hong Kong
3 years
Description
1,10 Phenanthroline Monohydrate: A Comprehensive Guide
1,10 Phenanthroline monohydrate is a versatile and fascinating compound with a myriad of applications, perfect for commercial and industrial settings alike. It is a prized compound widely used in various fields, such as analytical chemistry, industrial manufacturing, and biomedical research.
This robust compound boasts of a molecular formula C12H8N2.H2O and an assigned CAS number 5144-89-8. It has a molecular weight of 198.22 and is typically presented as a fine, white crystalline powder.
Key Features and Applications
- 1,10 Phenanthroline monohydrate's distinctive ability to forge a stable, orange complex with ferrous ions in a pH range of 4-5 makes it an ideal choice for iron content determination via spectrophotometry.
- Its unique chemistry enables it to engage in complex formations with various transition metals, yielding enduring chelates. These complexes and derivatives, notably those formed with copper, exhibit significant DNA cutting activity. This suggests potential technological uses in biotechnology as non-oxidizing nucleic acid cutting enzymes and possible therapeutic applications linked to anti-cancer activity.
- The compound, when recrystallized with water, retains one molecule of crystal water. Its properties include a melting point of 91.5 °C (198°F), solubility in ethanol, benzene, acetone, and an astounding boiling point above 360 °C (680 °F), features that continue to expand its range of uses.
- 1,10 Phenanthroline monohydrate has found immense utility as a quantitative colorimetric reagent for copper and iron. It can also function as an indicator during the titration of iron salt with cerium sulfate. Additionally, its potential use as a dye for animal fibers further broadens its scope of applications.
Safety Information
It is crucial to handle 1,10 Phenanthroline monohydrate properly due to its hazardous nature marked by risk terms R25 and R50/53. The compound is labeled with safety terms S45, S60, and S61, indicating that it should be handled with caution in all situations.
