UNC0064-12: Unlocking the Potential of Receptor Modulation

UNC0064-12, a captivating chemical compound with the CAS number 1430089-64-7, is a versatile and powerful tool in the realm of biochemical research and development. This small peptide, identified by the reference number 3D-FHC08964, holds the key to unlocking new frontiers in the understanding and manipulation of cellular signaling pathways. Its unique properties and diverse applications make it an invaluable asset for scientists and researchers seeking to push the boundaries of scientific discovery.

At the heart of UNC0064-12's significance lies its ability to modulate the receptor for the protein FGF2 (Fibroblast Growth Factor 2). By binding to the same site on the receptor as FGF2, this compound effectively blocks the binding of the natural ligand, preventing the activation of downstream signaling cascades. This targeted inhibition of the FGF2 receptor opens up a world of possibilities in the development of novel therapeutics and the exploration of cellular mechanisms.

But UNC0064-12's versatility extends beyond its role as an FGF2 receptor inhibitor. This remarkable compound has also been shown to act as a ligand for various ion channels, proteins that form pores in cell membranes to allow the passage of ions and molecules. By binding to these receptors, UNC0064-12 can induce changes in membrane potential, leading to observable increases in intracellular calcium levels within treated cells. This multifaceted functionality positions UNC0064-12 as a valuable tool in the investigation of ion channel biology and its implications in diverse physiological processes.

Unraveling the Chemical Composition

UNC0064-12 is a small peptide with the molecular formula C19H24N8, weighing in at 364.46 g/mol. Its high purity, with a minimum of 95% as determined by analytical methods, ensures reliable and consistent results in research applications. The compound's unique chemical structure, identified by the MDL number MFCD28385887, further contributes to its versatility and potential for innovative applications.

Classified under the HS code 2933599590, UNC0064-12 falls within the broader category of Biochemicals and Reagents, making it a valuable asset for researchers working in the fields of biology, pharmacology, and beyond. Its solubility, stability, and other physicochemical properties can be crucial factors in determining its suitability for specific experimental setups and chemical reactions.

Exploring the Potential Applications

The diverse capabilities of UNC0064-12 open up a wide range of potential applications, each with the promise of advancing scientific understanding and driving innovation.

Pharmaceutical Research: As an inhibitor of the FGF2 receptor, UNC0064-12 holds promise in the development of novel therapeutic agents targeting a variety of health conditions. Its ability to modulate cellular signaling pathways may lead to the discovery of new drug candidates with improved efficacy and specificity.

Ion Channel Investigations: The compound's ability to act as a ligand for ion channels presents exciting opportunities for researchers studying the role of these proteins in cellular function and disease. By leveraging UNC0064-12's influence on membrane potential and calcium homeostasis, scientists can gain deeper insights into the underlying mechanisms governing ion channel biology.

Biochemical Assays and Screening: UNC0064-12's unique properties make it a valuable tool in the design and optimization of biochemical assays and screening platforms. Researchers can utilize this compound to probe the dynamics of receptor-ligand interactions, explore the regulation of signaling pathways, and identify potential therapeutic targets.

Responsible Handling and Storage

Given the specialized nature of UNC0064-12, it is essential to handle and store the compound with the utmost care and attention to safety. While specific hazard information is not provided, it is recommended to follow standard laboratory safety protocols when working with this chemical. This includes wearing appropriate personal protective equipment, such as gloves, lab coats, and eye protection, and ensuring adequate ventilation during handling.