Rilmakalim: Unlocking the Power of Potassium Channel Regulation

Rilmakalim, a potent and highly selective potassium channel opener, stands as a remarkable chemical compound with the potential to revolutionize various fields of research and development. With its CAS number 132014-21-2 and product reference TM-T26086, this versatile molecule offers a unique opportunity to unlock new frontiers in the realms of pharmacology, cardiovascular science, and beyond.

At the heart of Rilmakalim's allure lies its ability to modulate potassium channel activity, a crucial mechanism in regulating cellular processes. By selectively activating these channels, Rilmakalim demonstrates a potent antivasoconstrictor effect, making it a valuable tool for researchers investigating cardiovascular health and function. This property holds immense promise in the development of innovative therapies targeting conditions such as hypertension, ischemic heart disease, and other vascular disorders.

Unraveling the Technical Specifications

Rilmakalim, with its chemical formula C21H23NO5S and a molecular weight of 401.48 g/mol, is a solid compound that boasts a purity of 100%. Its distinct color and form make it easily identifiable, while its solubility in various solvents ensures versatility in experimental settings.

Researchers can confidently rely on the long-term storage capabilities of Rilmakalim, which can be stored as a powder at -20°C for up to 3 years or in solvent at -80°C for 1 year, ensuring the compound's stability and integrity over time. This attention to detail underscores the commitment to providing researchers with a high-quality, reliable product that can withstand the rigors of scientific exploration.

Unlocking the Potential: Rilmakalim in Action

Rilmakalim's versatility extends beyond its technical specifications, as it has demonstrated remarkable potential in various applications. In in vitro studies, the compound has been shown to dose-dependently activate whole-cell currents in ventricular rat myocytes, with a concentration for half-maximal activation (EC50) of 1.1 μM and a Hill coefficient of 3.1. This data highlights Rilmakalim's potent and selective interaction with potassium channels, making it a valuable tool for researchers investigating the underlying mechanisms of cardiovascular function and dysfunction.

Beyond its cardiovascular applications, Rilmakalim's unique properties may also hold promise in other areas of scientific inquiry. Its ability to modulate ion channel activity could potentially be leveraged in the development of novel therapeutic agents, neurological research, or even the exploration of new materials with enhanced performance characteristics.

Navigating the Landscape: Safety and Handling

As with any specialized chemical compound, the safe handling and storage of Rilmakalim are of paramount importance. While no specific hazard information is currently available, it is crucial to adhere to standard laboratory safety protocols when working with this substance. This includes wearing appropriate personal protective equipment, such as gloves, lab coats, and eye protection, and ensuring proper ventilation during any handling or experimentation.

For long-term storage, Rilmakalim should be kept in a cool, dry environment, preferably at -20°C for the powder form or -80°C for solutions. Maintaining these optimal conditions will help preserve the compound's stability and purity, ensuring reliable results in your research endeavors.

Unlocking the Future: Rilmakalim's Potential

As researchers delve deeper into the world of Rilmakalim, the possibilities for groundbreaking discoveries and advancements become increasingly exciting. This potent potassium channel opener holds the key to unlocking new frontiers in cardiovascular science, pharmacology, and beyond. By leveraging its unique properties and carefully navigating its handling and storage requirements, scientists can unlock the full potential of Rilmakalim, paving the way for innovative solutions to pressing challenges in the scientific community.

Embrace the power of Rilmakalim and embark on a journey of scientific exploration, where the boundaries of knowledge are constantly pushed, and the promise of progress shines brightly.