N-Desmethyl Citalopram-d4 Oxalate

Introducing N-Desmethyl Citalopram-d4 Oxalate, a highly specialized and meticulously crafted chemical compound that holds immense value for researchers and scientists across various fields. With the CAS number 62498-68-4 and the reference number 4Z-C-096, this compound is a crucial player in the realm of antidepressant research and development.

As a deuterated analog of the active metabolite of the antidepressant drug citalopram, N-Desmethyl Citalopram-d4 Oxalate offers a unique perspective for researchers delving into the complexities of mood disorders and their pharmacological interventions. Its molecular structure, featuring a deuterium-labeled N-desmethyl group, provides a valuable tool for studying the pharmacokinetics and metabolism of citalopram, ultimately contributing to the advancement of more effective and targeted antidepressant therapies.

This off-white solid compound, with a molecular weight of 314.40 g/mol and a chemical formula of C19H15FN2OD4·C2H2O4, boasts a high level of purity and precision. Its carefully controlled synthesis ensures consistent and reliable results, making it an indispensable asset for researchers in the field of antidepressant research and development.

Key Features and Applications

• Antidepressant Research: N-Desmethyl Citalopram-d4 Oxalate serves as a crucial analytical standard and reference material for the study of citalopram metabolism and pharmacokinetics. Its deuterated structure allows for the precise tracking and quantification of the active metabolite, enabling researchers to gain deeper insights into the mechanisms of action and optimization of antidepressant therapies.
• Metabolic Studies: This compound is invaluable in conducting in vitro and in vivo studies on the metabolism of citalopram, a widely prescribed antidepressant. By utilizing the deuterium-labeled N-desmethyl group, researchers can accurately monitor the formation and disposition of the active metabolite, leading to a better understanding of the drug's pharmacokinetic profile and potential for optimization.
• Analytical Method Development: N-Desmethyl Citalopram-d4 Oxalate serves as a reliable reference standard in the development and validation of analytical methods, such as liquid chromatography-mass spectrometry (LC-MS) techniques. Its use ensures the accurate quantification and identification of the N-desmethyl metabolite in biological samples, supporting the advancement of analytical capabilities in the field of antidepressant research.

Safety and Handling

N-Desmethyl Citalopram-d4 Oxalate is classified as a hazardous substance, with several associated hazard statements (H302, H312, H315, H319, H332) and precautionary statements (P261, P271, P280, P302+P352, P305+P351+P338). It is essential to handle this compound with appropriate personal protective equipment, such as gloves, protective clothing, and eye protection, and to work in a well-ventilated area. Avoid breathing in the dust, fumes, gas, mist, vapors, or spray. In case of accidental exposure, follow the recommended first aid measures and seek medical attention if necessary.

Storage and Handling

For optimal stability and preservation of the compound's integrity, N-Desmethyl Citalopram-d4 Oxalate should be stored refrigerated, as specified in the Certificate of Analysis. Keep the container tightly closed in a dry and well-ventilated place to maintain its high quality and purity over the long term.

Disclaimer

It is important to note that this product is intended for laboratory use only and is not meant for human consumption. Researchers and scientists should exercise caution and adhere to all relevant safety protocols when