ICA-121431: A Potent Nav1.7 Channel Inhibitor for Innovative Research

Unlock the potential of ICA-121431, a nanomolar potent small molecule Nav1.7 channel inhibitor with an impressive IC50 of 19 nM for the rat Nav1.7 channel. This remarkable compound, identified by the CAS number 313254-51-2, offers researchers a valuable tool for exploring the intricate world of ion channels and their role in various physiological and pathological processes.

ICA-121431 stands out as a highly selective and potent inhibitor, exhibiting little to no activity against the human Nav1.5 or Nav1.7 channels. This selectivity makes it a prime candidate for investigating the therapeutic potential of Nav1.7 channel modulation, a promising avenue for addressing a wide range of health conditions, from pain management to neurological disorders.

Unraveling the Complexity of Ion Channels

Ion channels, such as the Nav1.7 sodium channel, play a crucial role in regulating cellular functions and signaling pathways. By precisely controlling the flow of ions across cell membranes, these channels contribute to the generation and propagation of electrical impulses, which are essential for nerve function, muscle contraction, and various other physiological processes.

ICA-121431 presents researchers with a powerful tool to delve deeper into the intricate mechanisms governing ion channel activity. Its nanomolar potency and selectivity for the Nav1.7 channel allow for the exploration of the channel's involvement in pain perception, neuronal excitability, and other related pathways. This knowledge can pave the way for the development of innovative therapeutic strategies targeting specific ion channel dysfunctions.

Exceptional Chemical Properties

ICA-121431 boasts a chemical formula of C23H19N3O3S2, with a molecular weight of 449.55 g/mol. Its high purity, measured at 98%, ensures reliable and consistent results in your research endeavors.

The compound's solid form and distinct color make it easily identifiable and straightforward to handle. Its solubility characteristics allow for versatile applications in various experimental settings, enabling researchers to explore its potential in diverse research areas.

Navigating Safety and Handling

While ICA-121431 is a powerful research tool, it is essential to exercise caution when handling this compound. It is classified as harmful if swallowed and may cause serious eye irritation. Additionally, it has the potential to cause long-lasting harmful effects to aquatic life.

To ensure the safety of researchers and the environment, adhere to the recommended handling and storage guidelines. Wear appropriate personal protective equipment, such as gloves, eye protection, and a face mask, when working with ICA-121431. Dispose of the compound and its waste in accordance with local, regional, and national regulations to minimize the impact on the environment.

Unlock the Potential of ICA-121431

Embark on your research journey with ICA-121431, a remarkable Nav1.7 channel inhibitor that offers a unique opportunity to unravel the complexities of ion channel biology. Leverage its exceptional potency and selectivity to explore innovative therapeutic approaches, advance our understanding of neurological processes, and contribute to the development of groundbreaking discoveries.

Explore the wealth of resources available, including technical data, safety information, and relevant scientific literature, to maximize the impact of your research endeavors. Unlock the potential of ICA-121431 and push the boundaries of what is possible in the realm of ion channel research.

• CAS Number: 313254-51-2
• Product Name: ICA-121431
• Reference Number: TM-T7336
• Description: ICA-121431 is a nanomolar potent small molecule Nav1.7 channel inhibitor with an IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1