Gabazine: A Potent GABA Receptor Antagonist for Groundbreaking Research

Gabazine, also known as SR95531, is a highly specialized chemical compound that has garnered significant attention in the scientific community. This GABA Receptor antagonist, with the CAS number 104104-50-9, is a valuable tool for researchers delving into the intricate workings of the central nervous system and the complex mechanisms underlying various neurological processes.

At its core, Gabazine is a powerful antagonist of GABAA receptors, exhibiting a binding affinity (Ki) in the range of 74-150 nM. This selective interaction with the GABA receptor subtype makes Gabazine an indispensable asset in the exploration of GABA-mediated neurotransmission and its role in physiological and pathological conditions. Whether you're investigating the fundamental principles of neuronal signaling or seeking to unravel the underlying causes of neurological disorders, Gabazine provides a crucial window into the dynamic interplay between GABA and its receptors.

Exceptional Purity and Technical Specifications

Gabazine, with its Ref # TM-T7622, is a meticulously crafted compound that boasts an impressive purity of 98.2%. Its chemical formula, C15H18BrN3O3, and a molecular weight of 368.23 g/mol, ensure a high degree of consistency and reliability in your research endeavors.

This solid compound, with a distinct color and form, has a flash point of 240.7°C, making it suitable for a wide range of experimental conditions. Its exceptional quality and technical specifications make Gabazine an indispensable tool for researchers seeking to push the boundaries of scientific discovery.

Versatile Applications in Neuroscience Research

The versatility of Gabazine extends far beyond its core function as a GABAA receptor antagonist. This compound has demonstrated efficacy against GABAA receptor isoforms from mice, rats, and humans, making it a valuable asset in cross-species studies and translational research.

In the realm of neuroscience, Gabazine has found widespread applications in the investigation of various neurological processes and disorders. Researchers have utilized this compound to study the role of GABA-mediated signaling in areas such as synaptic transmission, neuronal excitability, and the modulation of neuronal networks. By selectively blocking GABAA receptors, Gabazine provides a powerful tool to dissect the intricate mechanisms underlying neurological function and dysfunction, paving the way for groundbreaking discoveries and advancements in the field.

Optimal Storage and Handling

To ensure the long-term stability and integrity of Gabazine, it is recommended to store the powder form at -20°C for up to 3 years. If dissolved in a suitable solvent, the compound can be stored at -80°C for up to 1 year.

When handling Gabazine, it is crucial to adhere to standard laboratory safety protocols. Appropriate personal protective equipment, such as gloves, lab coat, and eye protection, should be worn to minimize the risk of exposure. Additionally, working in a well-ventilated area or outdoors is recommended to prevent the inhalation of dust, fumes, or vapors.

Unlocking the Potential of Gabazine in Your Research

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Whether you're investigating the fundamental mechanisms of neuronal communication, exploring the pathophysiology of neurological disorders, or developing innovative therapeutic strategies, Gabazine stands as a powerful tool to advance your research endeavors. Embrace the potential of this remarkable compound and embark on a journey of scientific discovery that could