Clozapine EP Impurity D

Clozapine EP Impurity D, with the CAS number 65514-71-8, is a highly specialized and meticulously crafted chemical compound that plays a crucial role in the world of pharmaceutical research and development. This off-white solid substance, with its molecular formula C18H21ClN4O and a molecular weight of 344.84 g/mol, is a valuable asset for scientists and researchers seeking to unlock new frontiers in the field of active pharmaceutical ingredients (APIs).

As an impurity associated with the antipsychotic drug clozapine, Clozapine EP Impurity D holds immense significance in the pharmaceutical industry. Its unique chemical structure and properties make it an indispensable tool for researchers, enabling them to explore the complexities of drug development and ensure the safety and efficacy of pharmaceutical products.

The compound's versatility extends beyond its primary application in the pharmaceutical realm. Clozapine EP Impurity D also finds use in the synthesis of other chemical compounds, contributing to the advancement of various scientific disciplines, from material science to organic chemistry. Its ability to serve as a building block or a key intermediate in complex reactions underscores its importance in the broader scientific community.

Product Features and Specifications

• CAS Number: 65514-71-8
• Molecular Formula: C18H21ClN4O
• Molecular Weight: 344.84 g/mol
• Physical Appearance: Off-White Solid
• Purity: Meets the requirements of the European Pharmacopoeia (EP) standards

Handling and Safety Considerations

Clozapine EP Impurity D is classified as a hazardous substance, with the following hazard statements and precautionary statements:

Hazard Statements: H302: Harmful if swallowed. H312: Harmful in contact with skin. H315: Causes skin irritation. H319: Causes serious eye irritation. H332: Harmful if inhaled.

Precautionary Statements: P261: Avoid breathing dust, fumes, gas, mist, vapours, spray. [As modified by IV ATP]. P271: Use only outdoors or in a well-ventilated area. P280: Wear protective gloves/protective clothing/eye protection/face protection. P302+P352: IF ON SKIN: Wash with plenty of soap and water. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

Storage and Handling Guidelines

To maintain the integrity and purity of Clozapine EP Impurity D, it is essential to adhere to the following storage and handling guidelines:

- Keep the product refrigerated as specified in the Certificate of Analysis. - Store the container tightly closed in a dry and well-ventilated place. - Avoid exposure to direct sunlight, heat, and moisture, as these factors can compromise the compound's stability and performance. - Handle the product with care, using appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety glasses. - Dispose of the product and its containers in accordance with local regulations and environmental guidelines.

Research and Development Applications

Clozapine EP Impurity D is primarily intended for laboratory use and research purposes. It is not meant for human consumption or any other direct application. Researchers and scientists can utilize this compound in a variety of ways, including but not limited to:

- Pharmaceutical research: Studying the impurity profile of clozapine and its potential impact on drug safety and efficacy. - Analytical method development: Developing and validating analytical techniques for the detection and quantification of Clozapine EP Impurity D. - Synthetic chemistry: Employing the compound as a building block or intermediate in the synthesis of other pharmaceutical