XL413: Selective Inhibitor of CDC7 Kinase

REF #: 3199514
Procurenet
Short description

XL413 is a selective inhibitor of the serine-threonine kinase CDC7, a regulator of cell cycle checkpoint control. It has been implicated in protecting DNA replication forks from destabilization during replication stress. With its chemical formula Cu2081u2085Hu2081u2081ClNu2084O and molecular weight 302.73 g/mol, XL413 is a white to off-white powder that exhibits a purity of u226598% (HPLC).

Key features:

  • Product Name: XL413
  • CAS Number: 1169562-71-3
  • Appearance: White to off-white powder
  • Solubility: Soluble in DMSO
  • Storage: Store at -20u00b0C
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Description

XL413: Selective Inhibitor of CDC7 Kinase

XL413 is a highly potent and selective inhibitor of the serine-threonine kinase CDC7. CDC7 is a crucial regulator of cell cycle checkpoint control and is implicated in protecting the genome during DNA replication. XL413 is designed to target CDC7 kinase, providing researchers with a powerful tool for studying cell cycle progression and DNA replication.

Key Features:

  • Product Name: XL413
  • CAS Number: 1169562-71-3
  • Chemical Formula: Cu2081u2085Hu2081u2081ClNu2084O
  • Molecular Weight: 302.73 g/mol
  • Purity: u226598% (HPLC)
  • Appearance: White to off-white powder
  • Solubility: Soluble in DMSO
  • Storage: Store at -20u00b0C

Detailed Information:

XL413 exhibits exceptional potency and selectivity towards CDC7 kinase, making it an ideal probe compound for use in various cellular and biochemical assays. The compound is carefully synthesized to ensure a high level of purity, guaranteeing consistent and reliable results. It is available as a white to off-white powder, allowing for easy handling and storage.

CDC7 kinase is a serine-threonine kinase that plays a critical role in regulating cell cycle progression. It functions by phosphorylating key substrates involved in DNA replication, effectively coordinating the replication process and maintaining genomic stability. By selectively inhibiting CDC7 kinase, XL413 offers researchers a valuable tool to investigate the mechanisms underlying cell cycle control and DNA replication.

Applications

XL413 can be employed in various applications, including:

  • Cell cycle research
  • DNA replication studies
  • Cancer research
  • Target identification and validation
  • Drug discovery and development

Handling and Storage

XL413 is soluble in DMSO, providing researchers with flexibility in experimental design. It is recommended to prepare a concentrated stock solution in an appropriate solvent, aliquot, and store at -20u00b0C. Avoid repeated freeze/thaw cycles, as it may compromise the integrity of the compound.

Safety Information

When handling XL413 or any other research chemical, it is essential to take appropriate safety precautions. Always wear suitable protective clothing and gloves when working with the compound. Ensure proper ventilation in the working area and avoid inhalation or ingestion. Dispose of any unused material according to local regulations.

XL413, with its high potency and selectivity towards CDC7 kinase, opens up exciting avenues for studying cell cycle control and DNA replication. As a trusted provider of research chemicals, we guarantee the quality, purity, and reliability of our products. Purchase XL413 today and enhance your research capabilities in the field of cell biology and DNA replication.

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