Spautin-1 (C43) - Potent Inhibitor of USP10 and USP13

REF #: 3199667
Short description
  • Spautin-1 (C43) is a potent inhibitor of two ubiquitin-specific peptidases, USP10 and USP13.
  • Increases the proteasomal degradation of class III PI3 kinase complexes.
  • Purity of 98% (HPLC).
  • Excellent choice for molecular biology and drug discovery applications.
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Spautin-1 (C43) - Potent Inhibitor of USP10 and USP13 for Molecular Biology and Drug Discovery

Product Description:

Spautin-1 (C43) is a highly potent inhibitor widely used in molecular biology and drug discovery. This compound effectively inhibits two ubiquitin-specific peptidases, USP10 and USP13, leading to increased proteasomal degradation of class III PI3 kinase complexes. With a purity level of 98% (HPLC), Spautin-1 (C43) offers a high-quality solution for various research applications.


  • Chemical Name: Spautin-1
  • Chemical Formula: C43
  • Purity: 98% (HPLC)
  • CAS Number: 1262888-28-7

Key Features:

  • Potent inhibitor of USP10 and USP13
  • Increases proteasomal degradation of class III PI3 kinase complexes
  • High purity level of 98% (HPLC)
  • Unique chemical structure


Spautin-1 (C43) is a unique compound that has gained significant attention in the field of molecular biology and drug discovery due to its exceptional inhibitory properties. By effectively inhibiting USP10 and USP13, two important ubiquitin-specific peptidases, this compound enhances the proteasomal degradation of class III PI3 kinase complexes. This mechanism of action makes Spautin-1 (C43) a valuable tool for studying various biological processes and exploring potential therapeutic applications.

With a purity level of 98% (HPLC), Spautin-1 (C43) ensures reliable and consistent results in research experiments. This high level of purity minimizes the risk of unwanted impurities interfering with experimental outcomes, making it an ideal choice for molecular biology and drug discovery studies.


  • Molecular biology
  • Cell biology
  • Drug discovery
  • Cancer research

Through its potent inhibition of USP10 and USP13, Spautin-1 (C43) offers researchers the opportunity to explore the intricate mechanisms regulating various biological processes. It is a valuable tool for investigating the roles of class III PI3 kinase complexes in different cellular pathways and for identifying potential therapeutic targets.

Chemical Structure:

Chemical Structure

The chemical structure of Spautin-1 (C43) is unique and carefully designed to achieve its potent inhibitory effects. This small molecule is composed of 43 carbon atoms, arranged in a specific configuration that interacts with the target enzymes, USP10 and USP13. The unique chemical structure of Spautin-1 (C43) contributes to its specificity and selectivity, making it an essential tool for investigating cellular processes and developing novel therapeutics.


For optimal preservation of Spautin-1 (C43), it is recommended to store the compound in a cool and dry place, away from direct sunlight and moisture. To prevent any contamination or degradation, the compound should be tightly sealed when not in use. Following these storage recommendations ensures the longevity and quality of the product, ensuring consistent performance in research experiments.


  • Wearing appropriate protective clothing, gloves, and eyewear
  • Working in a well-ventilated area
  • Avoiding direct contact with skin, eyes, and clothing
  • Using the compound only for intended research purposes

Adhering to these precautions ensures a safe working environment and minimizes the risk of accidental exposure to Spautin-1 (C43).

Handling and Disposal:

Spautin-1 (C43) should be handled with caution to prevent accidental spills or releases. In the event of any spills, it is necessary to clean up the area using suitable absorbent material. Proper disposal of Spautin-1 (C43) should be conducted in accordance with local regulations and guidelines for the disposal of hazardous chemicals. Responsible handling and disposal contribute to a safe research environment and protect the environment.

Regulatory Information:

As a chemical compound, Spautin-1 (C43) may be subject to specific regulations and restrictions in different regions. It is the responsibility of the user to comply with all applicable laws and regulations regarding the purchase, storage, handling, and disposal of this compound. Familiarize yourself with the regulations in your region to ensure legal and safe use of Spautin-1 (C43).

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