S3226 98 (HPLC) - Potent and Selective Inhibition of NHE3

REF #: 3199503
Short description

S3226 98 (HPLC)

  • Composition: 3,3′-(4-Methyl-1,2-phenylene)bis[N-(aminoiminomethyl)-2-methyl-2-propenamide] dihydrochloride
  • Purity: >98% (HPLC)
  • Application: Potent and selective NHE3 (NHE-3) inhibitor
  • Usage: Ideal for studying NHE3 in cultures and in animals in vivo
  • Inhibition activity: IC50 = 20 nM/human NHE3
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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S3226 98 (HPLC) - Potent and Selective Inhibition of NHE3

The S3226 98 (HPLC) is a high-quality compound used in scientific research for its potent and selective inhibition of NHE3 (NHE-3). It is composed of 3,3'- (4-Methyl-1,2-phenylene)bis[N-(aminoiminomethyl)-2-methyl-2-propenamide] dihydrochloride, which has been carefully synthesized to ensure its purity and effectiveness.

The purity of the S3226 98 (HPLC) compound is guaranteed to be at least 98% (HPLC). This high level of purity is essential for accurate and reliable research results, as impurities can interfere with the activity of the compound and lead to false conclusions. Through rigorous quality control measures, the purity of each batch of S3226 98 (HPLC) is verified, providing scientists with confidence in its performance.

Features and Benefits

  • Potent and Selective: The S3226 98 (HPLC) compound is specifically designed to target and inhibit NHE3. Its high potency allows for the effective inhibition of NHE3 activity, providing researchers with a powerful tool for studying its function.
  • Wide Range of Applications: The S3226 98 (HPLC) compound can be used in various applications, both in vitro and in vivo. It is commonly used in cell culture experiments to investigate the role of NHE3 in cellular processes. Additionally, it can be administered to animals for in vivo studies, allowing researchers to explore the effects of NHE3 inhibition in a whole organism.
  • Reliable Inhibition Activity: The S3226 98 (HPLC) compound exhibits strong inhibition activity against human NHE3, with an IC50 (half maximal inhibitory concentration) of 20 nM. This high level of inhibition ensures that researchers can achieve significant and measurable effects when studying NHE3 function.


  • 3,3'- (4-Methyl-1,2-phenylene)bis[N-(aminoiminomethyl)-2-methyl-2-propenamide] dihydrochloride


  • Investigating the role of NHE3 in cellular processes such as ion transport and pH regulation
  • Examining the effects of NHE3 inhibition on cell growth, differentiation, and apoptosis
  • Studying the involvement of NHE3 in specific diseases or pathological conditions

With its potent and selective inhibition of NHE3, the S3226 98 (HPLC) compound provides researchers with a valuable tool for understanding the function and significance of this transporter. Its high purity and reliability ensure accurate and reproducible results, making it an essential compound in the field of NHE3 research.

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