S14161 (8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran) - High-Quality Compound for Research

REF #: 3199832
Short description

S14161 (8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran)

  • Purity: 98% (HPLC)
  • Inhibits D-cyclin transactivation
  • Inhibition of phosphoinositide 3-kinase (PI3K) activity

Other names: SML1571, 8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran, 8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene, Pichromenen

CAS number: 883046-50-2

Quantity :
  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
Delivery options
  • 7 Days Return Back Policy
  • 2 Days Cancellation Policy
  • Ship Only

S14161 (8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran) is a high-quality product with a purity of 98% as determined by high-performance liquid chromatography (HPLC) analysis. It is a potent compound that exhibits several valuable properties, making it a versatile tool for research and development purposes. This extensive description will provide further details on the composition, features, and potential applications of S14161.


  • S14161, also known by its other names SML1571, 8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran, 8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene, and Pichromene, has a CAS number of 883046-50-2. With its unique chemical structure, it offers a range of biological activities and mechanisms of action that can be advantageous for various applications.

Features and Benefits:

  • Inhibition of D-cyclin transactivation: S14161 has been shown to effectively inhibit D-cyclin transactivation, a process that plays a critical role in cell cycle progression. By interfering with this mechanism, S14161 can help researchers gain a better understanding of cell cycle regulation and potentially contribute to the development of novel therapeutic strategies.
  • Suppression of phosphoinositide 3-kinase (PI3K) activity: PI3K is a key enzyme involved in various cellular processes, including cell growth, survival, and metabolism. S14161 has been found to inhibit PI3K activity, making it a valuable tool for investigating PI3K signaling pathways and its implications in diseases such as cancer, diabetes, and cardiovascular disorders.


  • Cell cycle studies: S14161's ability to inhibit D-cyclin transactivation makes it an essential compound for investigating cell cycle progression and the underlying regulatory mechanisms. It can be employed in cell culture experiments, cell synchronization studies, and cell cycle analysis assays.
  • Signal transduction research: The suppression of PI3K activity by S14161 allows researchers to explore the complex signaling pathways associated with PI3K and its downstream effectors. This compound can be used for investigating PI3K-related signaling cascades, such as the AKT/mTOR pathway, which is involved in cell survival, proliferation, and metabolism.
  • Drug discovery and development: S14161's unique features make it an attractive candidate for drug discovery and development efforts. By targeting D-cyclin transactivation and PI3K activity, researchers can evaluate the compound's potential as a therapeutic agent against diseases characterized by dysregulated cell cycle or PI3K signaling, such as cancer.
  • Mechanistic studies: S14161 can be employed in various mechanistic studies to elucidate the underlying molecular mechanisms of D-cyclin transactivation and PI3K signaling pathways. Its high purity ensures accurate and reliable results, allowing for a deeper understanding of these critical biological processes.

In conclusion, S14161 (8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran) is a highly pure compound that inhibits D-cyclin transactivation and PI3K activity. With its potent properties, it can serve as a valuable tool for researchers and scientists involved in cell cycle studies, signal transduction research, drug discovery, and mechanistic investigations. Its versatility and potential applications make it an indispensable compound in the field of life sciences and pharmaceutical research.

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