RO5256390 (S)-4-((S)-2-phenyl-butyl)-45-dihydro-oxazol-2-ylamine - TAAR1 Agonist | Neuroscience Research

REF #: 3199673
Short description
  • Chemical Name: (S)-4-((S)-2-phenyl-butyl)-4,5-dihydro-oxazol-2-ylamine
  • Purity: ≥98% (HPLC)
  • Function: TAAR1 agonist
  • Description: RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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RO5256390 (S)-4-((S)-2-phenyl-butyl)-45-dihydro-oxazol-2-ylamine

  • Chemical Name: (S)-4-((S)-2-phenyl-butyl)-4,5-dihydro-oxazol-2-ylamine
  • Purity: u226598% (HPLC)
  • Function: TAAR1 agonist

RO5256390 (S)-4-((S)-2-phenyl-butyl)-45-dihydro-oxazol-2-ylamine, also known by its chemical name, is a pharmacological compound that has gained significant attention in neuroscience research. It is widely used as an experimental tool to understand the role of Trace amine-associated receptor 1 (TAAR1) and its interactions with various neurotransmitter systems in the brain.

The purity of RO5256390 is guaranteed to be at least 98%, as assessed by high-performance liquid chromatography (HPLC). This ensures that researchers can confidently utilize this compound in their experiments without the concerns of impurities affecting the results. Its high purity also allows for accurate dosing and reliable data generation, which are crucial in scientific studies.

One of the key functions of RO5256390 is its ability to act as a TAAR1 agonist. TAAR1 is a G-protein coupled receptor that is primarily expressed in the brain. It is known to modulate the activity of various neurotransmitters, including dopamine and norepinephrine. By acting as an agonist, RO5256390 can activate TAAR1, leading to downstream effects on these neurotransmitter systems.

The unique chemical structure of RO5256390, characterized by its oxazole and amine functional groups, allows for specific interactions with the TAAR1 receptor. This interaction triggers a cascade of signaling events within the brain, which ultimately influence neurotransmission and neuronal activity. By studying the effects of RO5256390 on TAAR1, researchers can gain valuable insights into the role of TAAR1 in various physiological and pathological conditions.

RO5256390 is particularly valuable in neuroscience research due to its selective agonistic activity on TAAR1. Its specificity towards TAAR1 minimizes the potential for off-target effects, ensuring that the observed actions are primarily attributed to TAAR1 activation. This specificity is essential for accurately studying the role of TAAR1 and its interactions with other neurotransmitter systems.

In addition to its selective activity, RO5256390 is also highly potent. Its high potency allows researchers to use lower concentrations of the compound, reducing the potential for non-specific effects and increasing experimental control. This is particularly crucial in studies where precise modulation of TAAR1 activity is required to elicit specific responses.

Furthermore, RO5256390's pharmacological profile makes it ideal for in vitro and in vivo experiments. Its stability and solubility properties enable convenient administration through different routes, allowing researchers to explore its effects in various experimental models. This versatility enhances the potential applications of RO5256390 in studying TAAR1 function and investigating its role in different physiological and pathological contexts.

In summary, RO5256390 (S)-4-((S)-2-phenyl-butyl)-45-dihydro-oxazol-2-ylamine is a high-purity pharmacological compound that acts as a TAAR1 agonist. Its chemical structure, specificity, and potency make it a valuable tool for neuroscience research. Whether investigating the role of TAAR1 in neurophysiology, neuropsychiatry, or other areas of neuroscience, RO5256390 offers researchers a reliable and precise means to study this important receptor and its interactions with neurotransmitter systems in the brain.

Note: This product is for research use only and must not be used for human or animal consumption.

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