Proteasome Substrate II Fluorogenic - Highly Sensitive Fluorogenic Proteasome Substrate

REF #: 3199904
Procurenet
Short description

Proteasome Substrate II, Fluorogenic

A highly effective and sensitive fluorogenic proteasome substrate, Proteasome Substrate II is designed for studying proteasome activity. It can be used in various applications such as screening proteasome inhibitors or assessing proteasome activity in complex biological samples.

Key Features:

  • Fluorogenic proteasome substrate
  • Highly sensitive
  • Allows accurate measurement of proteasome activity
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

Proteasome Substrate II, Fluorogenic

The Proteasome Substrate II, Fluorogenic is a highly effective and sensitive fluorogenic proteasome substrate that is specifically designed for studying proteasome activity. It is a valuable tool that can be used in various applications such as screening proteasome inhibitors or assessing proteasome activity in complex biological samples.

Key Features:

  • Fluorogenic proteasome substrate: The Proteasome Substrate II is a fluorogenic substrate that emits a fluorescent signal upon proteasome cleavage, allowing for convenient measurement of proteasome activity.
  • Highly sensitive: This substrate is highly sensitive, enabling the detection of even low levels of proteasome activity with exceptional accuracy.
  • Allows accurate measurement of proteasome activity: The Proteasome Substrate II provides researchers with a reliable method for accurately measuring and quantifying proteasome activity in biological samples.

Synonyms: Proteasome Substrate II, Fluorogenic, Z-LLE-AMC

The Proteasome Substrate II is a fluorogenic substrate that contains the peptide sequence Z-LLE-AMC, which is conjugated with a fluorescent 7-amino-4-methylcoumarin (AMC) moiety. Upon proteasome cleavage, the substrate is hydrolyzed, resulting in the release of the AMC fluorophore. The released AMC emits a strong fluorescence signal, which can be conveniently detected and quantified using appropriate instrumentation.

This highly sensitive and specific substrate enables researchers to study proteasome activity in a wide range of biological systems and samples. It can be used to assess proteasome activity in cultured cells, tissue lysates, or purified enzyme preparations. Additionally, it is a valuable tool for screening proteasome inhibitors or evaluating the effectiveness of potential drug candidates on proteasome activity.

Specifications:

  • Product Name: Proteasome Substrate II, Fluorogenic
  • Product Code: 539141
  • Appearance: Pale yellow solid
  • Molecular Formula: C27H37N5O6
  • Molecular Weight: 523.62 g/mol
  • Storage Conditions: Store at -20u00b0C

The Proteasome Substrate II, Fluorogenic is supplied as a pale yellow solid, and it should be stored at -20u00b0C to maintain its stability and activity.

To learn more about the Proteasome Substrate II, including its material safety data sheet (MSDS), related peer-reviewed papers, technical documents, and similar products, please visit the official website using the provided product code: 539141.

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