PF-04457845 - Highly Effective Chemical Compound for Pharmaceutical Research

REF #: 3199857
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Short description

PF-04457845 – Highly Effective Chemical Compound for Pharmaceutical Research

  • Chemical name: N-(3-pyridazinyl)-4-(3-[5-trifluoromethyl-2-pyridinyloxy]benzylidene)piperidine-1-carboxamide
  • Molecular formula: C25H20F3N5O2
  • Formula weight: 483.45
  • Purity: 98% (HPLC)
  • Potency: Potent irreversible FAAH inhibitor
  • Mode of action: PF-04457845 is a potent, orally active, irreversible inhibitor of fatty acid amide hydrolase (FAAH), the principle enzyme involved in the degradation of the endocannabinoid anandamide
  • CAS number: 1020315-31-4
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

PF-04457845 - Highly Effective Chemical Compound for Pharmaceutical Research

PF-04457845 is a highly effective chemical compound widely used as a potent irreversible fatty acid amide hydrolase (FAAH) inhibitor in the field of pharmaceutical research and development.

Chemical Information

  • Chemical name: N-(3-pyridazinyl)-4-(3-[5-trifluoromethyl-2-pyridinyloxy]benzylidene)piperidine-1-carboxamide
  • Molecular formula: C25H20F3N5O2
  • Formula weight: 483.45
  • CAS number: 1020315-31-4

Composition

PF-04457845 is composed of Carbon (C), Hydrogen (H), Nitrogen (N), Oxygen (O), Fluorine (F), and other carefully selected organic compounds.

Features and Benefits

  • Purity: With a purity level of 98% as determined by High-Performance Liquid Chromatography (HPLC), PF-04457845 ensures effectiveness and reliability in experimental applications.
  • Potency: PF-04457845 is an exceptionally potent FAAH inhibitor, offering superior performance in inhibiting the enzymatic degradation of the endocannabinoid anandamide.
  • Mode of action: Acting as an orally active and irreversible FAAH inhibitor, PF-04457845 allows for the accumulation of anandamide, leading to enhanced endocannabinoid signaling and potential therapeutic benefits.
  • Versatility: PF-04457845 can be employed in a wide range of experimental setups and research projects, making it an indispensable tool for investigating the role of endocannabinoids and FAAH inhibition in various biological processes.

Applications

  • Neuropharmacology research: PF-04457845 is extensively used in studies exploring the therapeutic potential of enhancing endocannabinoid signaling in neurological functions and disorders such as pain management, epilepsy, anxiety, and neurodegenerative diseases.
  • Drug discovery: As a valuable tool in the development of novel drugs targeting the endocannabinoid system, PF-04457845 aids in understanding the effects of modulating endocannabinoid levels and signaling pathways.
  • Pharmacokinetic studies: PF-04457845 assists in the analysis of the distribution, metabolism, and excretion of endocannabinoids and related compounds, facilitating the study of pharmacokinetic properties and potential drug interactions associated with endocannabinoid modulation.

With its exceptional potency, purity, and versatility, PF-04457845 is an indispensable compound for researchers in the fields of neuropharmacology, drug discovery, and pharmacokinetic studies, offering numerous opportunities to explore the therapeutic potential of endocannabinoid modulation.

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