Madrasin (DDD00107587) - Highly Potent and Cell Penetrant Splicing Inhibitor

REF #: 3199629
Procurenet
Short description


Madrasin (DDD00107587) – Highly Potent and Cell Penetrant Splicing Inhibitor

  • Chemical formula: C20H20N4O2
  • Purity: >98% (HPLC)
  • Mode of action: Interferes with early stages of spliceosome assembly
  • Also known as: SML1409 or 2-(7-Methoxy-4-methyl-quinazolin-2-ylamino)-5, 6-dimethyl-3H-pyrimidin-4-one
  • Other names:
    • 2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-5, 6-dimethyl-4(1H)-pyrimidinone (9CI)
    • 4(1H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5, 6-dimethyl-(9CI)
    • 4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5, 6-dimethyl-


$0
Quantity :
  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
Delivery options
  • 7 Days Return Back Policy
  • 2 Days Cancellation Policy
  • Ship Only
Description

Madrasin (DDD00107587) - Highly Potent and Cell Penetrant Splicing Inhibitor

Madrasin (CAS number: 374913-63-0) is a highly potent and cell penetrant splicing inhibitor. Its chemical formula is C20H20N4O2, and it has a purity of over 98% as determined by High-Performance Liquid Chromatography (HPLC).

Features and Benefits:

  • Madrasin specifically targets and interferes with the early stages of spliceosome assembly, making it a powerful inhibitor for splicing research.
  • This small molecule compound exhibits excellent cell permeability, allowing it to easily penetrate cell membranes and exert its inhibitory effects.
  • With a purity of over 98%, Madrasin ensures high quality and reliable results in various experimental settings.

Applications:

Madrasin is widely used in molecular biology and drug discovery research for its ability to block splicing, a crucial process in gene expression. Some of the key applications of Madrasin include:

  • Studying spliceosome assembly: Madrasin inhibits the formation of the spliceosome, allowing researchers to investigate the underlying mechanisms of splicing and identify potential therapeutic targets.
  • Investigating alternative splicing: By selectively inhibiting splicing with Madrasin, researchers can study the impact of alternative splicing on gene expression, protein diversity, and cellular function.
  • Developing anti-cancer therapies: Madrasin's inhibition of spliceosome assembly makes it a valuable tool for understanding splicing dysregulation in cancer development and potentially identifying new therapeutic targets.

Chemical Structure:

Madrasin, also known as SML1409 or 2-(7-Methoxy-4-methyl-quinazolin-2-ylamino)-5, 6-dimethyl-3H-pyrimidin-4-one, has the following chemical structure:

Madrasin Chemical Structure

Synonyms:

  • 2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-5, 6-dimethyl-4(1H)-pyrimidinone (9CI)
  • 4(1H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5, 6-dimethyl-(9CI)
  • 4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5, 6-dimethyl-

All categories
Filters