Latrunculin B - Marine Toxin for Actin Research

REF #: 3199654
Procurenet
Short description
  • Product Name: Latrunculin B – Marine Toxin for Actin Research
  • CAS Number: 76343-94-7
  • Synonyms: Latrunculin B, Latrunculia magnifica
  • Chemical Formula: Not Available
  • Description: Latrunculin B is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fold more potent than cytochalasins.
$0
Quantity :
  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
Delivery options
  • 7 Days Return Back Policy
  • 2 Days Cancellation Policy
  • Ship Only
Description

Latrunculin B - Marine Toxin for Actin Research

Unlock the secrets of actin dynamics with Latrunculin B - a highly potent marine toxin that inhibits actin polymerization and disrupts microfilament organization. Derived from the marine sponge Latrunculia magnifica, this unique compound offers a range of features and benefits for researchers in various fields.

Key Features:

  • High Potency: Latrunculin B is 10 to 100-fold more potent than cytochalasins, providing researchers with a highly effective tool for actin research.
  • Unique Mechanism of Action: By binding to monomeric actin, Latrunculin B prevents its incorporation into growing filaments, leading to the disruption of microfilament organization.
  • Cell-Permeable: With the ability to pass through cell membranes, Latrunculin B allows researchers to study its effects on intracellular actin dynamics.
  • Wide Range of Applications: Latrunculin B has been widely used in cell biology, neuroscience, and cancer research to investigate cellular processes dependent on actin dynamics.
  • Pure and High-Quality: Extracted and purified to ensure maximum purity and activity, Latrunculin B delivers reliable and reproducible results.

Applications:

  • Cell Biology Research: Study actin dynamics and the role of the actin cytoskeleton in cell motility, cell division, and cell signaling.
  • Neuroscience Research: Investigate the role of actin in neuronal development, synaptic plasticity, and axonal growth.
  • Cancer Research: Understand the impact of actin disruption on cancer cell behavior, invasion, and metastasis.
  • Drug Discovery: Explore actin-targeting drugs and identify potential leads for therapeutic development.

Usage Guidelines:

  • Preparation: Dissolve Latrunculin B in an appropriate solvent to obtain the desired concentration for experiments.
  • Storage: Store Latrunculin B at -20°C in a tightly sealed container to maintain stability and activity.
  • Working Concentration: Determine the optimal concentration through dose-response experiments based on the specific experimental setup and cell type.
  • Handling Precautions: Latrunculin B is a toxic compound that requires proper handling with personal protective equipment. Avoid inhalation, ingestion, and contact with skin or eyes.
All categories
Filters