GF 109203X hydrochloride - Highly Potent Inhibitor of Protein Kinase C

REF #: 3199797
Procurenet
Short description

GF 109203X hydrochloride – Highly Potent Inhibitor of Protein Kinase C

  • Chemical Formula: C32H29N3O2.HCl
  • Molecular Weight: 540.05 g/mol
  • CAS Number: 176504-36-2
  • Purity: ≥ 95%
  • Synonyms: B6292, 3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide hydrochloride

GF 109203X hydrochloride (Bisindolylmaleimide I) is a highly potent inhibitor of protein kinase C. It has been extensively used in various research studies and applications. Some key features of this product include:

  • Inhibitor of Protein Kinase C: GF 109203X hydrochloride effectively inhibits protein kinase C, an important enzyme involved in various cellular processes.
  • Proven Efficacy: It has been proven to effectively inhibit protein kinase C in human neuroblastoma-derived kelly cells, making it a reliable choice for related studies.
  • Collagen-Triggered Adenosine and ATP Secretion: GF 109203X hydrochloride has shown its ability to prevent collagen-triggered adenosine and ATP secretion, providing insights into cellular signaling mechanisms.
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    Hong Kong Hong Kong 3 years
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Description

GF 109203X hydrochloride - Highly Potent Inhibitor of Protein Kinase C

GF 109203X hydrochloride, also known as Bisindolylmaleimide I, is a highly potent inhibitor of protein kinase C. It has been extensively studied for its ability to inhibit protein kinase C in various cellular systems, including human neuroblastoma-derived kelly cells. This compound has also shown promising results in preventing collagen-triggered adenosine and three phosphate (ATP) secretion.

Key Features:

  • Chemical Formula: C32H29N3O2.HCl
  • Molecular Weight: 540.05 g/mol
  • CAS Number: 176504-36-2
  • Purity: ≥ 95%
  • Synonyms: B6292, 3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide hydrochloride

Chemical Formula and Molecular Weight:

GF 109203X hydrochloride has a chemical formula of C32H29N3O2.HCl and a molecular weight of 540.05 g/mol. This well-defined chemical composition ensures reproducibility and accurate dosing in experimental studies.

High Purity:

GF 109203X hydrochloride is supplied with a guaranteed purity of ≥ 95%. This high level of purity is crucial for ensuring accurate and reliable results in protein kinase C inhibition studies. The purity is determined using advanced analytical techniques, providing researchers with a high-quality product that meets their criteria for experimentation.

Synonyms:

GF 109203X hydrochloride is commonly known by its synonyms B6292 and 3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide hydrochloride. These alternative names can be useful when searching for the compound in scientific literature or databases.

The inhibitory action of GF 109203X hydrochloride on protein kinase C makes it an invaluable tool in related research. Protein kinase C is an enzyme that plays a crucial role in signal transduction pathways involved in various cellular processes such as cell growth, differentiation, and apoptosis. By specifically targeting and inhibiting this enzyme, researchers can gain a deeper understanding of its functions and potential therapeutic implications.

The unique structure of GF 109203X hydrochloride allows it to interact with protein kinase C and inhibit its enzymatic activity. This inhibition can be reversible or irreversible, depending on the specific experimental conditions and concentration used.

The effectiveness of GF 109203X hydrochloride in preventing collagen-triggered adenosine and ATP secretion further highlights its potential in various research areas, including the study of platelet function, intracellular signaling, and cardiovascular disorders. By modulating protein kinase C activity, this compound offers researchers the opportunity to explore new pathways and mechanisms of action that may ultimately lead to the development of novel therapeutic strategies.

In conclusion, GF 109203X hydrochloride is a powerful inhibitor of protein kinase C, with a range of potential applications in biochemical and biomedical research. Its high purity, well-defined chemical composition, and documented inhibitory effects make it a valuable tool for scientists aiming to delve deeper into the intricate world of signal transduction pathways and cellular processes. Whether studying protein kinase C or investigating new therapeutic targets, GF 109203X hydrochloride offers a reliable and efficient solution to facilitate groundbreaking discoveries.

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