FFN102 - pH-Responsive Fluorescent False Neurotransmitter

REF #: 3199383
Procurenet
Short description

This pH-responsive fluorescent false neurotransmitter, FFN102, is a versatile chemical compound used in various applications. With a purity of 98% (HPLC), it acts as a substrate for dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2). The chemical formula, 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one trifluoroacetate, ensures high quality and reliability.

  • Multi-purpose compound: Acts as a substrate for DAT and VMAT2, making it suitable for different research areas.
  • High purity: 98% purity (HPLC), ensuring consistent results.
  • pH-responsive: Exhibits responsive behavior based on pH changes, expanding its potential applications.
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

FFN102 - pH-Responsive Fluorescent False Neurotransmitter

FFN102 is a highly specialized pH-responsive fluorescent false neurotransmitter designed for research purposes. It acts as both a dopamine transporter substrate (DAT) and a substrate for vesicular monoamine transporter 2 (VMAT2), making it a valuable tool for studying neurotransmission and related processes. With a purity of 98% (HPLC), FFN102 ensures reliable and consistent results in various experimental settings.

Chemical Composition

The chemical formula of FFN102 is 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one trifluoroacetate. This unique composition provides FFN102 with its distinctive properties, enabling it to be used as a reliable and versatile research tool.

Product Details

  • Product Name: FFN102
  • Purity: 98% (HPLC)
  • CAS Number: 1234064-11-9
  • Alternate Names: SML1172, Mini 102, Mini102

Features and Benefits

  • pH-Responsiveness: FFN102 exhibits fluorescence changes in response to variations in pH, allowing researchers to monitor pH fluctuations and assess their impact on neurotransmitter transport.
  • Dual Substrate Properties: As both a dopamine transporter substrate (DAT) and a substrate for vesicular monoamine transporter 2 (VMAT2), FFN102 enables researchers to study multiple aspects of neurotransmission using a single compound.
  • High Purity: With a purity of 98% (HPLC), FFN102 ensures reliable and consistent results, minimizing experimental variability and enhancing data quality.
  • Wide Application Range: FFN102 can be used in various experimental techniques, including fluorescence microscopy, live cell imaging, and neurotransmitter release assays, providing flexibility for different research needs.
  • Easy Detection: The fluorescent properties of FFN102 allow for straightforward detection, visualization, and quantification of neurotransmitter transport and release, enabling detailed analysis of synaptic signaling.

Applications

  • Neurotransmitter Transport Studies: FFN102 can be used to investigate the mechanisms and dynamics of neurotransmitter transport, including dopamine transport via the dopamine transporter (DAT).
  • Live Cell Imaging: With its pH-responsive fluorescence, FFN102 enables researchers to visualize and monitor neurotransmitter vesicle dynamics and release in real-time.
  • Neurodegenerative Disorders: FFN102 can aid in the study of neurodegenerative disorders by providing insights into neurotransmitter dysregulation and dysfunction in disease models.
  • Drug Discovery: FFN102's ability to interact with the dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) makes it a valuable compound for drug discovery and the development of novel therapeutics targeting these transporters.

Storage and Handling

Proper storage and handling of FFN102 are crucial to maintain its stability and effectiveness:

  • Store FFN102 in a cool, dry place, away from direct light.
  • Avoid repeated freeze-thaw cycles, as they can compromise the integrity of the product.
  • Handle FFN102 with appropriate protective measures, such as gloves and safety goggles, to minimize potential risks.

With its unique pH-responsive properties, dual substrate capabilities, and high purity, FFN102 is a powerful tool that contributes to advancing our understanding of neurotransmission and related processes. Choose FFN102 for your research needs and unlock new insights into the complex world of neuronal communication.

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