Epitubicin HCL Injection - Effective Chemotherapeutic Agent for Cancer Treatment

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Procurenet
Short description

Epirubicin HCL Injection is a potent anthracycline-based chemotherapy drug, often used in combating various types of cancer. It is a semi-synthetic derivative of doxorubicin, made soluble and stable through its hydrochloride salt form, enabling secure intravenous administration. Common applications include:

  • Breast cancer: Used as part of adjuvant and neoadjuvant chemotherapy regimens or for treating metastatic breast cancer. It can be used as a single agent or combined with other chemotherapy drugs.
  • Gastric cancer: Deployed in combination with other chemotherapy agents for managing advanced gastric cancer and as part of perioperative chemotherapy.
  • Non-small cell lung cancer (NSCLC): Often used with other chemotherapy medications for the treatment of advanced NSCLC.
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

Epitubicin HCL Injection - A Potent Chemotherapeutic Agent

Epitubicin HCL Injection is a proven, efficient chemotherapeutic agent used in cancer treatment. It's significant in managing diverse types of cancers, particularly breast cancer, gastric cancer, lung cancer, and lymphomas.

  • Compound Name: Epitubicin Hydrochloride
  • Synonyms: Epitubicin HCL, Epirubicin hydrochloride
  • IUPAC Name: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride
  • CAS Number: 56390-09-1
  • Molecular Formula: C27H29NO11.HCl
  • Molecular Weight: 579.98 g/mol
  • Canonical SMILES: CC(=O)Oc1cc2c(cc1O[C@H]3C[C@@](CO)(C[C@@H](O3)N)O)c4c5c(c6c2c(c(c1c6ccc(c1O)OC)O)OC)C(=O)c(c(cc5O)OC)C(=O)C4.Cl
  • Boiling Point: 891.8±65.0 °C
  • Melting Point: 202-206 °C
  • Pharmacological Class: Anthracycline Topoisomerase Inhibitors
  • Routes of Exposure: Intravenous
  • Therapeutic Uses: Treating various cancers, specifically breast cancer

Epitubicin HCL Injection works by intercalating DNA, inhibiting the enzyme topoisomerase II and producing complex radicals that damage the DNA, causing cell death and diminishing cancer growth.

Please note, this product is strictly to be used under medical supervision. Side effects can occur, and drug interactions are possible. Be keen to follow all professional medical advice concerning the dosage and treatment duration. Contraindications include known hypersensitivity to Epirubicin, severe myocardial insufficiency, recent myocardial infarction, severe arrhythmias, previous treatments with high doses of Epitubicin and severe liver disease.

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