Elacridar | 98% HPLC Purity | Compound ID: SML0486

REF #: 3199704
Procurenet
Short description

Elacridar

  • 98% HPLC Purity
  • Chemical formula: C34H33N3O5
  • Molecular weight: 563.65 g/mol
  • Compound ID: SML0486
  • Other names: GF120918, GG918, GW0918

This compound is a featured product for ADME Tox research. It is used for studying drug absorption, distribution, metabolism, and elimination (ADME) as well as toxicity in various biological systems.

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    Hong Kong Hong Kong 3 years
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Description

Elacridar | 98% HPLC Purity | Compound ID: SML0486

  • Chemical Formula: C34H33N3O5
  • Molecular Weight: 563.65 g/mol
  • Other Names: GF120918, GG918, GW0918

Description

Elacridar is a high-quality compound known for its 98% HPLC purity. With a compound ID of SML0486, it is also referred to by various other names such as GF120918, GG918, and GW0918. This compound is a featured product for ADME Tox research, playing a crucial role in studying drug absorption, distribution, metabolism, and elimination (ADME), as well as toxicity in various biological systems.

Applications

Elacridar is primarily used in ADME Tox research, where it is widely applied in various biological systems to evaluate the bioavailability and toxicity of drugs. Its applications include:

  • Investigating the role of drug transporters in pharmacokinetics
  • Assessing drug-drug interactions
  • Evaluating the impact of efflux transporters in drug resistance
  • Studying the influence of P-glycoprotein (P-gp) on drug disposition in the body
  • Examining potential strategies to overcome multidrug resistance
  • Screening potential drug candidates for their permeability and cellular uptake

Composition

Elacridar has a complex molecular structure consisting of 34 carbon atoms, 33 hydrogen atoms, 3 nitrogen atoms, and 5 oxygen atoms.

Features

Elacridar offers several notable features that make it a preferred choice for ADME Tox research:

  • High Purity: Elacridar exhibits a remarkable 98% purity as determined by high-performance liquid chromatography (HPLC). This ensures reliable and accurate results in research experiments.
  • Wide Application: Elacridar finds extensive use in pharmaceutical, biotechnology, and academic laboratories investigating drug transport, metabolism, and toxicity due to its importance in ADME Tox studies.
  • Specificity: Elacridar is widely recognized for its selective inhibition of P-glycoprotein (P-gp), an efflux transporter involved in drug resistance. Its use allows researchers to gain insights into the impact of P-gp on drug disposition and develop strategies to circumvent multidrug resistance.
  • Reliable Performance: Extensive testing and validation ensure that Elacridar delivers optimal performance and reproducible results. Its consistent purity, stability, and quality make it a reliable compound for ADME Tox research.
  • Comprehensive Characterization: Elacridar comes with detailed characterization data, including its HPLC purity profile, chemical structure, and molecular weight. This information facilitates researchers in understanding the compound and its interactions with drug transporters.

Warning and Precautions

Elacridar should be handled with suitable precautions due to its potential hazards. Some general guidelines include:

  • Wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles when handling elacridar.
  • Work in a well-ventilated area or use fume hoods to minimize exposure to vapors or dust particles.
  • Store elacridar in a cool, dry place away from incompatible substances and sources of ignition.
  • Refer to the safety data sheet (SDS) for detailed information on handling, storage, and disposal methods.

In case of accidental exposure or ingestion, seek immediate medical attention and provide healthcare professionals with relevant information regarding the compound.

Conclusion

Elacridar, with its 98% HPLC purity, is a highly pure compound extensively used in ADME Tox research. It is widely applied in studying drug absorption, distribution, metabolism, and elimination in various biological systems. Its applications include investigating drug transporters, assessing drug-drug interactions, evaluating the impact of efflux transporters in drug resistance, studying the influence of P-gp on drug disposition, examining strategies to overcome multidrug resistance, and screening potential drug candidates for their permeability and cellular uptake. With its high purity, specificity, reliability, and comprehensive characterization, Elacridar has become an invaluable tool in the field of pharmacology and drug development. However, precautions must be taken when handling elacridar to ensure safety and prevent potential hazards.

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