Dp44mT = 98 HPLC 152095-12-0 | Highly Pure Thiosemicarbazone Compound

REF #: 3199519
Procurenet
Short description

Dp44mT = 98 HPLC 152095-12-0 | Highly Pure Thiosemicarbazone Compound

  • Dp44mT (2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide)
  • >= 98% HPLC
  • Cell-permeable iron chelator and top2a activity inhibitor
  • Featured product for Apoptosis research
  • Ideal for cell signaling studies
$0
Quantity :
  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
Delivery options
  • 7 Days Return Back Policy
  • 2 Days Cancellation Policy
  • Ship Only
Description

Dp44mT = 98 HPLC 152095-12-0 | Highly Pure Thiosemicarbazone Compound

Dp44mT is a highly pure compound with a minimum assay of 98% HPLC. Its chemical name is 2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide. This compound belongs to the family of thiosemicarbazones and is specifically classified as a ketonic thiosemicarbazone. It is commonly used in various cell signaling studies.

Features:

  • Cell-permeable iron chelator: Dp44mT has the ability to bind to and chelate iron ions. It can penetrate cell membranes, making it suitable for research involving iron homeostasis and its implications in cellular processes.
  • Top2a activity inhibitor: Dp44mT has been observed to inhibit the activity of topoisomerase 2-alpha (Top2a), an enzyme involved in DNA replication and repair. By inhibiting Top2a, Dp44mT can affect cell division and potentially induce apoptosis.

Composition and Structure:

The chemical formula of Dp44mT is C18H18N6S. It has a molecular weight of 354.44 g/mol. The compound consists of several functional groups, including pyridine rings and a hydrazinecarbothioamide moiety. The structural arrangement of Dp44mT allows for its unique interactions with target molecules in biological systems.

Dp44mT is also known as Di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone. Its CAS number is 152095-12-0, serving as a unique identifier in scientific literature and databases.

The high HPLC purity of Dp44mT ensures consistent and accurate results, minimizing experimental variability. Its purity is confirmed through high-performance liquid chromatography (HPLC) analysis, a widely accepted technique for assessing the quality of organic compounds.

As an iron chelator and Top2a activity inhibitor, Dp44mT offers researchers a valuable tool to investigate various cellular processes and signaling pathways. Its cell-permeability and targeted actions provide insights into the role of iron and Top2a in cell physiology, offering potential applications in the field of cancer research and drug development.

All categories
Filters