Dehydroleucodine: Mast Cell Stabilizing Compound for Pharmaceuticals, Cosmetics, and Nutraceuticals

REF #: 3199758
Procurenet
Short description

Dehydroleucodine: Mast Cell Stabilizing Compound for Pharmaceuticals, Cosmetics, and Nutraceuticals

  • Purity: 98% (HPLC)
  • Chemical formula: C15H16O4
  • CAS number: 36150-07-9
  • Key Features:
    • Derived from Artemisia douglasiana Besser
    • Mast cell stabilizer
  • Alternative Names:
    • D4196
    • 11, 13-Dehydroleucodin
    • Dehydroleucodin
    • Leucodin
    • Lidbeckialactone
    • Mesatlantin E
    • NSC 180034
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

Dehydroleucodine: Mast Cell Stabilizing Compound for Pharmaceuticals, Cosmetics, and Nutraceuticals

Dehydroleucodine is a highly pure sesquiterpene lactone derived from Artemisia douglasiana Besser. With its mast cell stabilizing properties, it finds applications across various industries, including pharmaceuticals, cosmetics, and nutraceuticals. This natural compound offers numerous benefits, such as anti-inflammatory activity and immune modulation, making it a valuable ingredient in the development of innovative products. As with any chemical compound, safe handling practices should be followed to ensure a secure working environment.

Key Features:

  • Purity: 98% (HPLC)
  • Chemical formula: C15H16O4
  • CAS number: 36150-07-9
  • Alternative Names:
    • - D4196
    • - 11, 13-Dehydroleucodin
    • - Dehydroleucodin
    • - Leucodin
    • - Lidbeckialactone
    • - Mesatlantin E
    • - NSC 180034
  • Composition and Structure:
  • Dehydroleucodine (C15H16O4) belongs to the class of sesquiterpene lactones. It possesses a unique chemical structure consisting of a fifteen-carbon backbone with a lactone ring. These structural features contribute to its biological activity and functional properties.

  • Uses and Applications:
  • Dehydroleucodine's mast cell stabilizing activity makes it a sought-after compound in various industries:

    • - Pharmaceuticals: Dehydroleucodine has shown potential in the treatment of various inflammatory conditions, including asthma, allergic rhinitis, and dermatitis. By inhibiting the release of inflammatory mediators from mast cells, it helps reduce allergic reactions and symptoms.
    • - Cosmetics: Due to its anti-inflammatory properties, dehydroleucodine is used in skincare formulations to soothe and calm irritated skin. It helps reduce redness, itching, and swelling, making it suitable for sensitive and reactive skin.
    • - Nutraceuticals: Dehydroleucodine is also incorporated into dietary supplements targeting inflammatory conditions. Its natural origin and ability to modulate the immune system make it an attractive option for individuals seeking natural alternatives for managing allergies and inflammation.
  • Mode of Action:
  • Dehydroleucodine exerts its mast cell stabilizing effects by inhibiting the release of inflammatory mediators, such as histamine, leukotrienes, and prostaglandins. It acts on multiple targets within mast cells, interfering with intracellular signaling pathways involved in the release of these mediators. By modulating these pathways, dehydroleucodine helps maintain mast cells' stability and prevents exaggerated immune responses.

  • Precautions and Handling:
  • As with any chemical compound, it is essential to follow safe handling practices when working with dehydroleucodine:

    • - Use personal protective equipment (PPE), including gloves and safety glasses, when handling dehydroleucodine.
    • - Store the compound in a cool, dry place away from direct sunlight and heat sources.
    • - Avoid inhalation, ingestion, or direct contact with the compound. In case of accidental exposure, rinse the affected area with plenty of water and seek medical attention if necessary.
    • - Dispose of any unused or waste material according to local regulations and guidelines.
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