CK-636 = 98% HPLC | High Purity Actin-Related Protein (Arp)2/3 Complex Inhibitor

REF #: 3199465
Short description
  • CK-636 = 98% HPLC
  • Description: CK-636 is a high-purity compound known for its ability to inhibit the activity of actin-related protein (Arp)2/3 complex.
  • Chemical Formula: C7374
  • CAS Number: 442632-72-6
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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CK-636 = 98% HPLC - High Purity Actin-Related Protein (Arp)2/3 Complex Inhibitor is a reliable and highly pure reagent used in various research applications. With a purity of 98% determined by HPLC analysis, CK-636 offers consistent and reliable results in research experiments.

CK-636, also known as CK-0944636 or N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide, is widely recognized for its ability to inhibit the activity of actin-related protein (Arp)2/3 complex, making it an important tool for studying the dynamics of actin cytoskeleton and cellular processes dependent on actin remodeling.

Key Features and Benefits:

  • High Purity: CK-636 offers a purity of 98% as determined by HPLC analysis, ensuring reliable and consistent results in research experiments.
  • Actin-Related Protein (Arp)2/3 Complex Inhibitor: CK-636 is known for its potent inhibitory activity against the Arp2/3 complex. This makes it an ideal research tool for studying actin dynamics, cellular morphogenesis, and other processes involving actin remodeling.
  • High-Performance Liquid Chromatography Tested: CK-636 undergoes rigorous testing using high-performance liquid chromatography (HPLC) to determine its purity and ensure batch-to-batch consistency.
  • Research Application: CK-636 is commonly used in various research applications, including cell biology, molecular biology, and biochemistry, to investigate the role of actin dynamics in different cellular processes.


  • Actin Dynamics Studies: CK-636 is frequently employed in studies investigating the regulation and dynamics of the actin cytoskeleton. It allows researchers to selectively inhibit the Arp2/3 complex, a key regulator of actin polymerization, thereby perturbing actin dynamics in cellular systems.
  • Cellular Morphogenesis: By targeting the Arp2/3 complex, CK-636 can be used to study cellular morphogenesis processes, including cell migration, vesicle trafficking, and cell shape changes. Understanding these fundamental cellular processes is essential in various fields, such as cancer research, immunology, and developmental biology.
  • Wound Healing and Tissue Repair: Actin dynamics play a crucial role in wound healing and tissue repair processes. CK-636's ability to selectively inhibit the Arp2/3 complex offers researchers a valuable tool in elucidating the mechanisms underlying these processes and developing potential therapeutic strategies.
  • Drug Discovery: CK-636 can contribute to drug discovery efforts by studying the effect of actin dynamics modulation on cellular processes. By understanding interplays between actin regulation and diseases, researchers can identify novel therapeutic targets and develop potential drugs for various pathologies.

Composition and Specifications:

Chemical Formula: C7374
CAS Number: 442632-72-6
Purity: 98% (HPLC)

Storage and Handling:

Storage: Store CK-636 at -20°C in a dry and well-ventilated area. Protect it from direct light sources.
Handling: Follow general laboratory precautions while handling CK-636. Avoid inhalation, ingestion, and contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical advice if needed.
Disposal: Dispose of CK-636 according to local regulations. Consult with appropriate regulatory agencies for specific guidelines.

Note: The information provided above is for reference purposes only. It is essential to carefully read and adhere to the product's instructions, specifications, and safety guidelines provided in the product's manual and labeling before using CK-636 in any research or experimental procedures.

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