Ciclosporin Soft Capsules: Pharmaceutical Solution for Preventing Transplant Rejection & GVHD

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Procurenet
Short description

Ciclosporin Soft Capsules are a high-quality pharmaceutical solution for the prevention of organ and bone marrow transplant rejection, and the treatment of graft versus host disease (GVHD).

  • A Pharmaceutical-Grade Treatment: Expertly crafted to ensure optimal results and patient safety.
  • Diverse Applications: Successfully prevents rejection post-transplantation and treats GVHD in its initial stages.
  • Worldwide Reach: Our distribution network extends to regions around the globe, ensuring timely delivery.
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
Description

Ciclosporin Soft Capsules: Pharmaceutical-Grade Solution for Transplant Rejection and GVHD

Ciclosporin Soft Capsules represent an advanced pharmacological intervention in organ transplantation and bone marrow transplantation. This pharmaceutical-grade drug is primarily employed to stave off rejection post-transplantation and to prevent and treat graft versus host disease (GVHD), especially at the initial stage.

  • Compound Name: Cyclosporine
  • Synonyms: Ciclosporin, Ciclosporina, Cyclosporin, Cyclosporin A, Cyclosporine A
  • IUPAC Name: Cyclic (4→2)-peptide of L-Ala, L-Leu, Gly, L-Val, 2-amino-6-octenoyl-L-α-amino-butyric acid, L-Me-Leu, D-Ala]
  • CAS Number: 59865-13-3
  • Molecular Formula: C62H111N11O12
  • Molecular Weight: 1202.61 g/mol
  • Mechanism of Action: Works by inhibiting calcineurin, a protein phosphatase which under normal circumstances induces the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital for the body's learned (adaptive) immune response.
  • Pharmacological Class: Immunosuppressant
  • Routes of Exposure: Oral
  • Therapeutic Uses: Primarily used in organ transplantation to prevent rejection. It achieves this by suppressing the activity of the patient's immune system.
  • Side Effects: Can include hypertension, gum hyperplasia, convulsions, peptic ulcers, pancreatitis, fever, vomiting, diarrhea, confusion, hypercholesterolemia, tingling and numbness, as well as potential liver and kidney damage.
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