c-KIT (D820E), Active, GST Tagged PRECISIO® - Product Description

REF #: 3199422
Short description

c-KIT (D820E), active, GST tagged PRECISIOu00ae

  • Recombinant c-KIT (D820E) protein expressed in baculovirus infected Sf9 cells
  • = 70% SDS-PAGE, buffered aqueous glycerol solution
  • Active, GST tagged
  • Synonyms: CD117, PBT, SCFR
  • CAS Number: 1537224-27-3
Quantity :
  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
Delivery options
  • 7 Days Return Back Policy
  • 2 Days Cancellation Policy
  • Ship Only

c-KIT (D820E), active, GST tagged PRECISIOu00ae

  • Product Description: The c-KIT (D820E) recombinant protein is a highly efficient and reliable protein expressed in baculovirus infected Sf9 cells. With its active and GST tagged properties, this protein offers exceptional performance and versatility for a wide range of research applications.
  • Composition: The protein is provided as a buffered aqueous glycerol solution, carefully optimized for high purity and stability. The protein has been extensively characterized using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis, confirming its integrity and purity. The protein purity is at least 70%, ensuring reliable results and reproducibility.
  • Features:
  • High Activity: The c-KIT (D820E) protein exhibits high enzymatic activity, allowing for accurate and efficient experimental results in various research areas.
  • GST Tagged: The protein is tagged with glutathione S-transferase (GST), enabling easy purification and efficient detection using anti-GST antibodies.
  • Recombinant Protein: The c-KIT (D820E) protein is produced using cutting-edge recombinant DNA technology, ensuring consistent and reliable performance.

The c-KIT protein, also known as CD117, PBT, or SCFR, plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. It is a transmembrane receptor tyrosine kinase belonging to the class III subfamily of receptor tyrosine kinases. The D820E mutation is linked to the development of certain types of cancers, making it of significant interest in cancer research.

Researchers can utilize the c-KIT (D820E) protein in a wide range of applications, including but not limited to:

  • Drug discovery and development
  • Cell signaling studies
  • Cancer research
  • Protein-protein interaction studies
  • Structural biology

With its high activity and reliability, the c-KIT (D820E) protein enables precise and accurate investigation of c-KIT signaling pathways, facilitating a deeper understanding of its role in various physiological and pathological conditions.

Storage and Handling

The c-KIT (D820E) protein should be stored at -80u00b0C upon receipt to ensure protein stability and preserve its activity. Thawing the protein on ice and aliquoting it into smaller quantities is recommended to avoid repeated freeze-thaw cycles, which may affect its activity. For detailed information on handling and precautions, please refer to the Material Safety Data Sheet (MSDS) provided. Additionally, you can find related peer-reviewed papers, technical documents, and similar products at SRP5299 to further explore the potential of c-KIT (D820E) protein in your research.

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