Bendamustine Hydrochloride Hydrate 98 (HPLC) - Treanda - Anticancer Drug

REF #: 3199891
Procurenet
Short description
  • Bendamustine Hydrochloride Hydrate 98 (HPLC) – Treanda is an effective anticancer drug used in the treatment of various cancers.
  • Contains >= 98% HPLC purity.
  • Part of LOPAC 1280, a biologically annotated collection of high-quality compounds.
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

Bendamustine hydrochloride hydrate 98 (HPLC), also known as Treanda, is a highly pure compound widely used in the research and pharmaceutical industries. This white to off-white crystalline powder belongs to the biologically annotated compound collection called LOPAC 1280, solidifying its importance in various biological studies and its potential as a valuable research tool.

Product Details:

  • IUPAC Name: 1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl monohydrochloride
  • Molecular Formula: C16H21Cl2N3O2
  • Molecular Weight: 358.27 g/mol
  • Purity: >= 98% (HPLC)
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in water and organic solvents
  • Storage: Store at -20°C in a dry and well-ventilated place
  • Shelf Life: The product is stable for at least 2 years from the date of receipt when stored as directed

Application:

  • Treatment of chronic lymphocytic leukemia (CLL): Bendamustine hydrochloride hydrate is a bifunctional alkylating agent commonly used as a single agent or in combination with other chemotherapeutic agents for the treatment of CLL. Its unique mechanism of action results in increased cancer cell death, making it an effective treatment option.
  • Treatment of non-Hodgkin lymphoma (NHL): Approved for the treatment of NHL, specifically for patients with relapsed or refractory disease. Clinical trials have shown high response rates and improved progression-free survival.
  • Combination therapy: Bendamustine hydrochloride hydrate is often combined with other drugs, such as rituximab, to enhance its efficacy in the treatment of various hematologic malignancies.
  • Research tool: Widely used in oncology and pharmacology studies to investigate the mechanism of action of anticancer agents and explore novel treatment strategies.

Handling and Safety:

  • Wear appropriate protective clothing, gloves, and eyewear when handling the compound
  • Observe good laboratory practices and follow all safety protocols
  • Store the compound in a securely closed container in a cool, dry, and well-ventilated area
  • Dispose of any unused or expired materials in accordance with local regulations
  • Avoid contact with skin, eyes, and clothing. In case of contact, rinse thoroughly with water and seek medical attention if necessary.

Bendamustine hydrochloride hydrate 98 (HPLC), commonly known as Treanda, is a highly pure compound with potent anticancer properties. Its use in the research and pharmaceutical industries, as well as its inclusion in the LOPAC 1280 collection, highlights its significance as a valuable research tool. With its well-established efficacy in treating chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL), this compound continues to play a crucial role in the development of novel treatment strategies and furthering our understanding of oncology. When handled and stored properly, Bendamustine hydrochloride hydrate offers researchers and clinicians a reliable and effective option in the fight against cancer.

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