ACT-462206 - 98% HPLC | Dual Orexin Receptor Antagonist

REF #: 3199842
Short description

ACT-462206 – 98% HPLC

  • Chemical Name: (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide
  • Purity: ≥ 98% (HPLC)
  • Description: ACT-462206 is an orally active, brain penetrant, potent and selective dual orexin1/2 receptor antagonist (DORA).
  • CAS Number: 1361321-96-1
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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ACT-462206 - 98% HPLC

  • Chemical Name: (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide
  • Purity: ≥98% (HPLC)
  • Description: ACT-462206 is an orally active, brain penetrant, potent and selective dual orexin1/2 receptor antagonist (DORA).
  • CAS Number: 1361321-96-1

The ACT-462206 is a high-quality chemical compound formulated with (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide. With a purity level of at least 98% as verified by HPLC analysis, this product is commonly used in research and development applications.

Features and Benefits:

  • Potency: ACT-462206 is a potent substance that exhibits its desired effects at a relatively low dosage.
  • Dual Orexin1/2 Receptor Antagonist: This compound acts as an antagonist for both orexin1 and orexin2 receptors. It selectively blocks the binding of orexin peptides to these receptors, resulting in the inhibition of orexin signaling pathways.
  • Brain Penetrant: ACT-462206 is designed to efficiently cross the blood-brain barrier, allowing it to reach its target site in the brain and exert its pharmacological effects.
  • Orally Active: This compound can be administered orally, providing convenience in experimental setups and potential therapeutic applications.

Chemical Information:

The chemical name of ACT-462206, (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide, describes its molecular structure and functional groups. It is a pyrrolidinecarboxamide derivative with substitutions on different positions of the phenyl and pyrrolidine rings, giving it specific properties and activity. The sulfonyl group adds to its overall structure and contributes to its pharmacological effects.

Usage and Applications:

ACT-462206 has been widely used in various research applications. Its role as a dual orexin1/2 receptor antagonist makes it valuable in studying the orexin system, which plays a crucial role in regulating wakefulness, arousal, appetite, and other physiological processes. By blocking the orexin receptors, researchers can investigate the specific functions and pathways influenced by these receptors.

Safety and Handling:

Although ACT-462206 is a potent compound, it is important to handle it with care to ensure safety and accurate results in experimental settings. The following precautions should be taken:

  • Use appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles when handling the compound.
  • Store the product in a cool, dry place away from direct sunlight and sources of ignition.
  • Avoid inhalation or ingestion and avoid contact with skin and eyes. In case of accidental contact, rinse thoroughly with water and seek medical attention if necessary.
  • Dispose of unused portions or waste material in accordance with local regulations and best laboratory practices.

For detailed information on safe handling, storage, and disposal, refer to the safety data sheet (SDS) provided by the supplier or manufacturer.

Overall, ACT-462206 is a valuable chemical compound that offers potent activity as a dual orexin1/2 receptor antagonist. With its high purity level of at least 98% (HPLC), researchers can rely on its consistency and accuracy in their studies. Whether investigating the orexin system or exploring its potential therapeutic applications, ACT-462206 provides a reliable tool for scientists and researchers.

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