7-Methylguanosine: Nucleoside Compound for RNA Metabolism and Gene Expression Regulation

REF #: 3200473
Procurenet
Short description
  • Chemical Name: 7-Methylguanosine
  • Usage: 7-Methylguanosine is commonly used to characterize and study the metabolism of naturally occurring methylated guanosines in RNAs, contributing to RNA metabolism and gene expression regulation.
  • Product Title: 7-Methylguanosine: Nucleoside Compound for RNA Metabolism and Gene Expression Regulation
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

7-Methylguanosine: Nucleoside Compound for RNA Metabolism and Gene Expression Regulation

7-Methylguanosine is a valuable tool for researchers studying the function and metabolism of methylated guanosines in RNAs. It belongs to the family of nucleosides, which are the building blocks of nucleic acids such as DNA and RNA. This compound is a methylated form of guanosine, with a methyl group attached to the 7th position of the guanine base, playing a crucial role in various biological processes, including RNA metabolism and gene expression regulation.

Product Details:

  • Chemical Name: 7-Methylguanosine
  • Chemical Formula: N/A
  • CAS Number: 20244-86-4
  • Purity: u226590%
  • Usage: 7-Methylguanosine is commonly used to characterize and study the metabolism of naturally occurring methylated guanosines in RNAs.

Features and Benefits:

  • High Purity: The product has a minimum purity of 90%, ensuring reliable and consistent results in experimental applications.
  • Specialized Applications: 7-Methylguanosine is particularly useful in studying the function and metabolism of naturally occurring methylated guanosines in RNAs.
  • Complementary to Other Nucleosides: It can be used in combination with other nucleosides or modified nucleosides to investigate their impact on RNA structure and function.
  • Structural Analysis: The presence of the methyl group in 7-Methylguanosine can be exploited for structural analysis and identification in various biochemical studies.
  • Gene Expression Regulation: 7-Methylguanosine plays a role in the regulation of gene expression by affecting RNA stability and translation efficiency.

Applications:

  • RNA Modification Studies: It is commonly used to investigate the role of methylated guanosines in RNA metabolism, including RNA splicing, stability, and translation.
  • RNA Epigenetics: 7-Methylguanosine contributes to the emerging field of RNA epigenetics, where modifications on RNA molecules play critical roles in gene expression regulation and cellular functions.
  • Functional Genomics: By altering the presence of 7-Methylguanosine in specific RNA molecules, researchers can assess its impact on RNA structure, function, and interaction with proteins or other nucleic acids.
  • RNA-Based Therapeutics: Understanding the influence of naturally occurring methylated guanosines in RNAs can provide valuable insights for the development of RNA-based therapeutics targeting diseases such as cancer and genetic disorders.
  • Biochemical Assays: 7-Methylguanosine can be used as a standard or reference compound in various biochemical assays, such as enzymatic activity assays or detection of methylated RNA species.

Storage and Handling:

  • Storage: Store the product at -20u00b0C in a dry and dark place to avoid degradation and contamination.
  • Handling: Handle the compound with appropriate precautionary measures, such as wearing protective gloves and eye protection.
  • Solubility: 7-Methylguanosine is soluble in water, and solutions can be prepared at desired concentrations for experimental use.

Overall, 7-Methylguanosine is an indispensable reagent for researchers studying the function and metabolism of methylated guanosines in RNAs. Its high purity, specialized applications, compatibility with other nucleosides, and role in gene expression regulation make it a valuable tool in various molecular biology and biochemical studies.

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