4-Octyl Itaconate Cell-permeable Derivative | Decreases Cytokine Production | High-Purity Compound

REF #: 3199651
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4-Octyl Itaconate Cell-permeable Derivative – Decreases Cytokine Production – High-Purity Compound

  • Chemical Formula: C14H22O4
  • Purity: ≥98% (HPLC)
  • Function: Cell-permeable itaconate derivative that decreases cytokine production and is protective against lipopolysaccharide-induced lethality in vivo
  • Macrophage Regulation: The endogenous metabolite itaconate has recently emerged as a regulator of macrophage function
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    Hong Kong Hong Kong 3 years
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Description

4-Octyl Itaconate Cell-permeable Derivative | Decreases Cytokine Production | High-Purity Compound

  • Chemical Formula: C14H22O4
  • Purity: ≥98% (HPLC)
  • Chemical Names: ≤-Monooctyl itaconate, 3-[(Octan-4-yloxy)carbonyl]but-3-enoate, 4-Octyl methylenesuccinate, -Octyl 3-carboxy-3-butenoate
  • Function: Cell-permeable itaconate derivative that decreases cytokine production and is protective against lipopolysaccharide-induced lethality in vivo
  • Macrophage Regulation: The endogenous metabolite itaconate has recently emerged as a regulator of macrophage function

4-Octyl Itaconate Cell-permeable Derivative is a high-purity compound with a chemical formula of C14H22O4. It is a cell-permeable itaconate derivative that has been shown to have significant effects on cytokine production and to provide protection against lipopolysaccharide-induced lethality in vivo. The compound, also known as ≤-Monooctyl itaconate, 3-[(Octan-4-yloxy)carbonyl]but-3-enoate, 4-Octyl methylenesuccinate, or -Octyl 3-carboxy-3-butenoate, has gained attention for its potential in regulating macrophage function.

Key Features:

  • Chemical Formula: C14H22O4
  • Purity: ≥98% (HPLC)
  • Cell-permeable itaconate derivative
  • Decreases cytokine production
  • Protective against lipopolysaccharide-induced lethality in vivo
  • Potential regulator of macrophage function

Chemical Formula:

4-Octyl Itaconate Cell-permeable Derivative has a chemical formula of C14H22O4. This formula indicates that the compound is made up of 14 carbon atoms, 22 hydrogen atoms, and 4 oxygen atoms. The specific arrangement and bonding of these atoms contribute to the unique properties and functions of 4-Octyl Itaconate Cell-permeable Derivative.

Purity: ≥98% (HPLC)

4-Octyl Itaconate Cell-permeable Derivative is a high-purity compound, with a purity of at least 98% as determined by HPLC (High-Performance Liquid Chromatography). This high level of purity ensures that the compound is free from impurities or contaminants and allows for reliable and consistent results when used in various applications.

Chemical Names:

4-Octyl Itaconate Cell-permeable Derivative is known by various chemical names, including ≤-Monooctyl itaconate, 3-[(Octan-4-yloxy)carbonyl]but-3-enoate, 4-Octyl methylenesuccinate, and -Octyl 3-carboxy-3-butenoate. These different names reflect the compound's chemical composition and structure, as well as its potential applications in different fields.

Function: Cell-permeable itaconate derivative that decreases cytokine production and is protective against lipopolysaccharide-induced lethality in vivo

4-Octyl Itaconate Cell-permeable Derivative is a cell-permeable derivative of itaconate that has been found to have specific functions and effects on biological systems. It has been shown to decrease cytokine production, which are signaling molecules involved in various immune and inflammatory responses. By modulating cytokine production, 4-Octyl Itaconate Cell-permeable Derivative may have potential therapeutic applications in conditions characterized by abnormal cytokine levels and dysregulated immune responses.

Additionally, 4-Octyl Itaconate Cell-permeable Derivative has been found to be protective against lipopolysaccharide-induced lethality in vivo. Lipopolysaccharide (LPS), also known as endotoxin, is a component found in the outer membrane of Gram-negative bacteria. It is a potent stimulator of the immune system and can induce strong inflammatory responses. The ability of 4-Octyl Itaconate Cell-permeable Derivative to protect against LPS-induced lethality suggests its potential in mitigating the harmful effects of bacterial infections and related inflammatory conditions.

Macrophage Regulation: The endogenous metabolite itaconate has recently emerged as a regulator of macrophage function

Macrophages are a type of immune cell that play a vital role in detecting and eliminating pathogens, as well as regulating inflammation. The endogenous metabolite itaconate has gained significant attention as a regulator of macrophage function. Itaconate and its derivatives, such as 4-Octyl Itaconate Cell-permeable Derivative, have been found to modulate various aspects of macrophage biology, including their polarization, cytokine production, and antimicrobial activity.

Through its effects on macrophages, 4-Octyl Itaconate Cell-permeable Derivative has the potential to influence immune responses and inflammatory processes. This may have implications for the development of novel therapeutic approaches for conditions characterized by dysregulated immune responses, such as autoimmune diseases, chronic inflammatory disorders, and certain types of cancer.

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