4-Hydroxymidazolam 59468-85-8: Key Features and Supplier Details

REF #: 3199806
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Short description

4-Hydroxymidazolam 59468-85-8: Key Features and Supplier Details

  • Chemical formula: C16H12ClFN3O
  • 8-Chloro-6-(2-fluorophenyl)-4-hydroxy-4H-imidazo[1,5a][1,4]bezodiazepine
  • Used in cell biology studies as a CYP3A4 metabolite of midazolam
  • Minor hydroxylated metabolite of Midazolam (MDZ)
  • High-quality raw material for the pharmaceutical industry
  • Reliable supplier offering competitive prices
  • Wide range of products available in the B2B marketplace
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  • Procurenet Team Tshim Sha Tsui
    Hong Kong Hong Kong 3 years
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Description

4-Hydroxymidazolam 59468-85-8: Key Features and Supplier Details

4-Hydroxymidazolam (C16H12ClFN3O) is a compound widely used in cell biology studies as a CYP3A4 metabolite of midazolam. With a molecular weight of 327.74 g/mol, it plays a significant role in investigating the metabolic pathways and mechanisms involved in midazolam's processing within cells. By studying the actions of 4-Hydroxymidazolam, researchers can gain a deeper understanding of the role and function of CYP3A4 enzymes in drug metabolism.

Chemical Structure:

  • Chemical formula: C16H12ClFN3O
  • Structure: 8-Chloro-6-(2-fluorophenyl)-4-hydroxy-4H-imidazo[1,5a][1,4]bezodiazepine

Key Features and Composition:

  • Compound type: Benzodiazepine metabolite
  • Primary use: Cell biology studies
  • Supplier details: Obtainable from authorized suppliers and distributors in the field of chemical research and development

Metabolite of Midazolam (MDZ):

4-Hydroxymidazolam is a minor hydroxylated metabolite of Midazolam (MDZ), a benzodiazepine drug commonly used as a sedative, anxiolytic, and hypnotic agent. Midazolam undergoes metabolism in the liver primarily through the cytochrome P450 enzyme system, specifically the CYP3A4 enzyme. The conversion of Midazolam into 4-Hydroxymidazolam occurs via a hydroxylation reaction catalyzed by the CYP3A4 enzyme. Along with several other metabolites of Midazolam, 4-Hydroxymidazolam contributes to the overall pharmacokinetics and elimination of Midazolam.

Supplier Details:

When sourcing 4-Hydroxymidazolam 59468-85-8, it is crucial to obtain it from reliable and trusted suppliers and distributors in the field of chemical research and development. This ensures the compound's quality, purity, and adherence to safety standards, thereby enabling accurate and reliable experimental results.

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