(1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-Methylbutanoate (Pravastatin Lactone)

In the ever-evolving world of pharmaceutical research and development, the compound (1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-Methylbutanoate, commonly known as Pravastatin Lactone, stands as a remarkable and versatile chemical entity. This highly purified compound, identified by the CAS number 85956-22-5, has garnered significant attention for its potential applications in the realm of drug discovery and development.

Pravastatin Lactone is a complex organic molecule with a unique molecular structure, featuring a hexahydronaphthalene core, a tetrahydropyran ring, and a methylbutanoate moiety. This intricate arrangement of functional groups and stereochemical configurations endows the compound with exceptional properties, making it a valuable asset in the pursuit of innovative pharmaceutical solutions.

Pharmaceutical Applications

The primary focus of Pravastatin Lactone's applications lies within the pharmaceutical industry. As a key intermediate in the synthesis of the widely-used statin drug Pravastatin, this compound plays a crucial role in the development of cholesterol-lowering medications. Researchers have leveraged its structural features to explore the creation of novel drug candidates targeting a range of cardiovascular and metabolic disorders.

Beyond its direct use in statin synthesis, Pravastatin Lactone's versatile nature allows it to serve as a versatile building block in the development of other pharmaceutical compounds. Its unique chemical properties and structural complexity make it a valuable starting material or reagent in the synthesis of a diverse array of therapeutic agents, potentially addressing a wide spectrum of health conditions.

Chemical Synthesis and Material Science

The exceptional purity and well-defined structure of Pravastatin Lactone also make it a valuable tool in the field of chemical synthesis. Researchers in material science and organic chemistry have leveraged this compound's reactivity and selectivity to explore the creation of novel materials and compounds with tailored properties. Its integration into various synthetic pathways can lead to the development of advanced materials with enhanced performance characteristics, such as improved thermal stability, mechanical strength, or optical properties.

The compound's IUPAC name, [(1S,3S,7S,8S,8aR)-3-hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate, provides a clear and comprehensive identification, while its InChI code, InChI=1S/C23H34O6/c1-4-13(2)23(27)29-20-11-16(24)9-15-6-5-14(3)19(22(15)20)8-7-18-10-17(25)12-21(26)28-18/h5-6,9,13-14,16-20,22,24-25H,4,7-8,10-12H2,1-3H3/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1, offers a unique identifier for researchers seeking detailed information about its molecular structure and properties.

Handling and Storage

Pravastatin Lactone is